Neuroendocrine tumors (NETs) of the abdomen are rare tumors with an incidence of 3.56 per 100,000 in the general population. Obesity is a growing public health problem with varying effects on the severities of other diseases. We investigated the association between obesity and inpatient morbidity/mortality in patients with abdominal NETs utilizing the Nationwide Inpatient Sample (NIS).Methods: We analyzed data from the NIS database to investigate the association between obesity and abdominal NETs using patient information from 22,096 patient discharges from January 1, 2009 to December 31, 2010.Results: We demonstrate that obesity is strongly associated with decreased rates of inpatient mortality in patients with NET (odds ratio [OR] = 0.6, multivariate P = .02) and that malnutrition is associated with a nearly 5-fold higher risk of inpatient mortality (multivariate P<.0005). We did not find a statistical interaction between obesity and malnutrition; however, patients who were both malnourished and obese had a lower mortality risk than purely malnourished patients.Conclusions: Our data suggests that nutritional status may be an important factor in inpatient mortality in patients with NETs, with obesity being protective.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism