Dense (aged) circulating red cells contain normal concentrations of adenosine triphosphate (ATP)

F. H. Kirkpatrick, A. G. Muhs, Raymond K Kostuk, C. W. Gabel

Research output: Contribution to journalArticle

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Abstract

The densest 0.1%-1% of circulating red cells were separated from fresh blood, and the ATP content of a representative sample of such cells was determined. The dense ('old') cells had decreased amounts of ATP relative to unfractionated cells. However, the dense cells were also smaller, and the concentration of ATP in these cells was the same as in controls. Therefore, it seems unlikely that loss of cellular ATP is a causative factor in removal of senescent red cells from the circulation.

Original languageEnglish (US)
Pages (from-to)946-950
Number of pages5
JournalBlood
Volume54
Issue number4
StatePublished - 1979
Externally publishedYes

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Adenosine Triphosphate
Cells
Blood

ASJC Scopus subject areas

  • Hematology

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Dense (aged) circulating red cells contain normal concentrations of adenosine triphosphate (ATP). / Kirkpatrick, F. H.; Muhs, A. G.; Kostuk, Raymond K; Gabel, C. W.

In: Blood, Vol. 54, No. 4, 1979, p. 946-950.

Research output: Contribution to journalArticle

Kirkpatrick, FH, Muhs, AG, Kostuk, RK & Gabel, CW 1979, 'Dense (aged) circulating red cells contain normal concentrations of adenosine triphosphate (ATP)', Blood, vol. 54, no. 4, pp. 946-950.
Kirkpatrick, F. H. ; Muhs, A. G. ; Kostuk, Raymond K ; Gabel, C. W. / Dense (aged) circulating red cells contain normal concentrations of adenosine triphosphate (ATP). In: Blood. 1979 ; Vol. 54, No. 4. pp. 946-950.
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