Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection

Molly Keenan, Tyler H. Tate, Khanh Kieu, John F. Black, Urs Utzinger, Jennifer K. Barton

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Early detection of ovarian cancer is only achieved in around 20% of women due to lack of effective screening. We propose a method for surveillance of high risk women based on a microendoscope introduced transvaginally to image the fallopian tubes and ovaries. This requires extreme miniaturization of the optics and catheter sheath. We describe the design of a falloposcope that combines optical coherence tomography (OCT) and wide field imaging into a sub-1 mm diameter package. We characterize the systems and show that they provide contrast on ex-vivo samples of ovary and fallopian tube. In addition, we show the mechanical performance of the endoscope in an anatomically correct model of the female reproductive tract.

Original languageEnglish (US)
Article number#279464
Pages (from-to)124-136
Number of pages13
JournalBiomedical Optics Express
Volume8
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • Endoscopic imaging
  • Medical optics instrumentation
  • ObGyn
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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