Design of a noninvasive blood glucose sensor

D. Nguyen, Meiling Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes the design of a non-invasive blood glucose testing device. The Monte Carlo Pulsed Photoacoustic simulation of Figure 1 with the skin optic model in Figure 2 suggests we will need at least a signal to noise ratio (SNR) of 10 4. This SNR adequate to resolve 1 mili-Mole (mM) glucose variation in a 1 mm path length aqueous solution as wanted by ISO DIS 15197 5. The needed pixel signal to noise ratio (SNR) is achieved with in pixel differential gain amplifier which provides the pixel conversion gain in mV/e-. The normal CMOS imager typical conversion gain is a few μV/e-. Further, we substantial reduce the pixel noise to KT / 100 Cpd (Figure 5) with MIAO active pixel reset scheme. The prior art of pixel noise are KT / 30 Cpd (Pain active reset - Figure 4 Ref 7) and KT / 18 Cpd (Fowler active reset - Figure 3 Ref 6). Where Cpd is the pixel diode capacitance, K is Boltzmann constant and T is the temperature.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
Pages56-59
Number of pages4
Publication statusPublished - 2012
Externally publishedYes
EventNanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 - Santa Clara, CA, United States
Duration: Jun 18 2012Jun 21 2012

Other

OtherNanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
CountryUnited States
CitySanta Clara, CA
Period6/18/126/21/12

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Keywords

  • Active reset
  • Diabetes
  • Monte Carlo simulation
  • Noninvasive glucose monitor
  • Pixel differential amplifier
  • Pulsed photoacoustic
  • Skin optics model

ASJC Scopus subject areas

  • Ceramics and Composites
  • Surfaces, Coatings and Films

Cite this

Nguyen, D., & Wang, M. (2012). Design of a noninvasive blood glucose sensor. In Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 (pp. 56-59)