Abstract
This paper describes the design of a non-invasive blood glucose testing device. The Monte Carlo Pulsed Photoacoustic simulation of Figure 1 with the skin optic model in Figure 2 suggests we will need at least a signal to noise ratio (SNR) of 10 4. This SNR adequate to resolve 1 mili-Mole (mM) glucose variation in a 1 mm path length aqueous solution as wanted by ISO DIS 15197 5. The needed pixel signal to noise ratio (SNR) is achieved with in pixel differential gain amplifier which provides the pixel conversion gain in mV/e-. The normal CMOS imager typical conversion gain is a few μV/e-. Further, we substantial reduce the pixel noise to KT / 100 Cpd (Figure 5) with MIAO active pixel reset scheme. The prior art of pixel noise are KT / 30 Cpd (Pain active reset - Figure 4 Ref 7) and KT / 18 Cpd (Fowler active reset - Figure 3 Ref 6). Where Cpd is the pixel diode capacitance, K is Boltzmann constant and T is the temperature.
| Original language | English (US) |
|---|---|
| Title of host publication | Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 |
| Pages | 56-59 |
| Number of pages | 4 |
| State | Published - 2012 |
| Externally published | Yes |
| Event | Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 - Santa Clara, CA, United States Duration: Jun 18 2012 → Jun 21 2012 |
Other
| Other | Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 |
|---|---|
| Country | United States |
| City | Santa Clara, CA |
| Period | 6/18/12 → 6/21/12 |
Fingerprint
Keywords
- Active reset
- Diabetes
- Monte Carlo simulation
- Noninvasive glucose monitor
- Pixel differential amplifier
- Pulsed photoacoustic
- Skin optics model
ASJC Scopus subject areas
- Ceramics and Composites
- Surfaces, Coatings and Films
Cite this
Design of a noninvasive blood glucose sensor. / Nguyen, D.; Wang, Meiling.
Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012. 2012. p. 56-59.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Design of a noninvasive blood glucose sensor
AU - Nguyen, D.
AU - Wang, Meiling
PY - 2012
Y1 - 2012
N2 - This paper describes the design of a non-invasive blood glucose testing device. The Monte Carlo Pulsed Photoacoustic simulation of Figure 1 with the skin optic model in Figure 2 suggests we will need at least a signal to noise ratio (SNR) of 10 4. This SNR adequate to resolve 1 mili-Mole (mM) glucose variation in a 1 mm path length aqueous solution as wanted by ISO DIS 15197 5. The needed pixel signal to noise ratio (SNR) is achieved with in pixel differential gain amplifier which provides the pixel conversion gain in mV/e-. The normal CMOS imager typical conversion gain is a few μV/e-. Further, we substantial reduce the pixel noise to KT / 100 Cpd (Figure 5) with MIAO active pixel reset scheme. The prior art of pixel noise are KT / 30 Cpd (Pain active reset - Figure 4 Ref 7) and KT / 18 Cpd (Fowler active reset - Figure 3 Ref 6). Where Cpd is the pixel diode capacitance, K is Boltzmann constant and T is the temperature.
AB - This paper describes the design of a non-invasive blood glucose testing device. The Monte Carlo Pulsed Photoacoustic simulation of Figure 1 with the skin optic model in Figure 2 suggests we will need at least a signal to noise ratio (SNR) of 10 4. This SNR adequate to resolve 1 mili-Mole (mM) glucose variation in a 1 mm path length aqueous solution as wanted by ISO DIS 15197 5. The needed pixel signal to noise ratio (SNR) is achieved with in pixel differential gain amplifier which provides the pixel conversion gain in mV/e-. The normal CMOS imager typical conversion gain is a few μV/e-. Further, we substantial reduce the pixel noise to KT / 100 Cpd (Figure 5) with MIAO active pixel reset scheme. The prior art of pixel noise are KT / 30 Cpd (Pain active reset - Figure 4 Ref 7) and KT / 18 Cpd (Fowler active reset - Figure 3 Ref 6). Where Cpd is the pixel diode capacitance, K is Boltzmann constant and T is the temperature.
KW - Active reset
KW - Diabetes
KW - Monte Carlo simulation
KW - Noninvasive glucose monitor
KW - Pixel differential amplifier
KW - Pulsed photoacoustic
KW - Skin optics model
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UR - http://www.scopus.com/inward/citedby.url?scp=84864968965&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84864968965
SN - 9781466562769
SP - 56
EP - 59
BT - Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
ER -