Detection of amphotericin B-resistant Candida isolates in a broth-based system

J. H. Rex, C. R. Cooper, W. G. Merz, John N Galgiani, E. J. Anaissie

Research output: Contribution to journalArticle

176 Citations (Scopus)

Abstract

Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.

Original languageEnglish (US)
Pages (from-to)906-909
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume39
Issue number4
StatePublished - 1995
Externally publishedYes

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Amphotericin B
Candida
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Detection of amphotericin B-resistant Candida isolates in a broth-based system. / Rex, J. H.; Cooper, C. R.; Merz, W. G.; Galgiani, John N; Anaissie, E. J.

In: Antimicrobial Agents and Chemotherapy, Vol. 39, No. 4, 1995, p. 906-909.

Research output: Contribution to journalArticle

Rex, J. H. ; Cooper, C. R. ; Merz, W. G. ; Galgiani, John N ; Anaissie, E. J. / Detection of amphotericin B-resistant Candida isolates in a broth-based system. In: Antimicrobial Agents and Chemotherapy. 1995 ; Vol. 39, No. 4. pp. 906-909.
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