Detection of atherosclerosis via magnetic resonance imaging

Andrew L. Alexander, Victor T. Pytlewski, Michael F. Brown, Arthur F. Gmitro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetic resonance imaging (MRI) of atherosclerotic lipids using a stimulated-echo diffusion- weighted (STED) sequence is demonstrated. The STED sequence exploits the large difference in diffusion between lipid (primarily cholesteryl ester) and water. The optimization of the STED sequence is discussed. The results of lipid imaging are corroborated with nuclear magnetic resonance (NMR) spectroscopy. This technique is non-invasive, and therefore, it is potentially useful in following the progression of the disease in animal models and in humans.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsGeorge S.M.D. Abela
PublisherPubl by Int Soc for Optical Engineering
Pages26-33
Number of pages8
ISBN (Print)0819407887
StatePublished - Dec 1 1992
EventDiagnostic and Therapeutic Cardiovascular Interventions II - Los Angeles, CA, USA
Duration: Jan 19 1992Jan 20 1992

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1642
ISSN (Print)0277-786X

Other

OtherDiagnostic and Therapeutic Cardiovascular Interventions II
CityLos Angeles, CA, USA
Period1/19/921/20/92

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Alexander, A. L., Pytlewski, V. T., Brown, M. F., & Gmitro, A. F. (1992). Detection of atherosclerosis via magnetic resonance imaging. In G. S. M. D. Abela (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 26-33). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1642). Publ by Int Soc for Optical Engineering.