Development of an implantable artificial lung: Challenges and progress

Joseph B. Zwischenberger, Carryn M. Anderson, Keith E. Cook, Scott D Lick, Lyle F. Mockros, Robert H. Bartlett

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Unlike dialysis, which functions as a bridge to renal transplantation, or a ventricular assist device, which serves as a bridge to cardiac transplantation, no suitable bridge to lung transplantation exists. Our goal is to design and build an ambulatory artificial lung that can be perfused entirely by the right ventricle and completely support the metabolic O2 and CO2 requirements of an adult. Such a device could realize a substantial clinical impact as a bridge to lung transplantation, as a support device immediately post-lung transplant, and as a rescue and/or supplement to mechanical ventilation during the treatment of severe respiratory failure. Research on the artificial lung has focused on the design, mode of attachment to the pulmonary circulation, and intracorporeal versus paracorporeal placement of the device.

Original languageEnglish (US)
Pages (from-to)316-320
Number of pages5
JournalASAIO Journal
Volume47
Issue number4
StatePublished - 2001
Externally publishedYes

Fingerprint

Lung Transplantation
Equipment and Supplies
Lung
Heart-Assist Devices
Pulmonary Circulation
Heart Transplantation
Transplantation (surgical)
Artificial Respiration
Respiratory Insufficiency
Kidney Transplantation
Transplants
Heart Ventricles
Dialysis
Research
Therapeutics

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering

Cite this

Zwischenberger, J. B., Anderson, C. M., Cook, K. E., Lick, S. D., Mockros, L. F., & Bartlett, R. H. (2001). Development of an implantable artificial lung: Challenges and progress. ASAIO Journal, 47(4), 316-320.

Development of an implantable artificial lung : Challenges and progress. / Zwischenberger, Joseph B.; Anderson, Carryn M.; Cook, Keith E.; Lick, Scott D; Mockros, Lyle F.; Bartlett, Robert H.

In: ASAIO Journal, Vol. 47, No. 4, 2001, p. 316-320.

Research output: Contribution to journalArticle

Zwischenberger, JB, Anderson, CM, Cook, KE, Lick, SD, Mockros, LF & Bartlett, RH 2001, 'Development of an implantable artificial lung: Challenges and progress', ASAIO Journal, vol. 47, no. 4, pp. 316-320.
Zwischenberger JB, Anderson CM, Cook KE, Lick SD, Mockros LF, Bartlett RH. Development of an implantable artificial lung: Challenges and progress. ASAIO Journal. 2001;47(4):316-320.
Zwischenberger, Joseph B. ; Anderson, Carryn M. ; Cook, Keith E. ; Lick, Scott D ; Mockros, Lyle F. ; Bartlett, Robert H. / Development of an implantable artificial lung : Challenges and progress. In: ASAIO Journal. 2001 ; Vol. 47, No. 4. pp. 316-320.
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