Development of delta opioid peptides as nonaddicting analgesics

R. S. Rapaka, Frank Porreca

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Although much effort has been devoted to opioid research since the identification of enkephalins, understanding of the physiological importance and mechanisms of action of endogenous opioids lags behind understanding of opiate alkaloids such as morphine. In recent years, several novel approaches have been refined with promise for the successful development of the long-awaited nonaddicting analgesics that act at the opioid delta receptor. The present communication reviews these efforts.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalPharmaceutical Research
Volume8
Issue number1
DOIs
StatePublished - 1991

Fingerprint

Opioid Peptides
Opioid Analgesics
Analgesics
Opiate Alkaloids
delta Opioid Receptor
Enkephalins
Morphine
Communication
Research

Keywords

  • Delta opioid peptides
  • Drug development Peptide drugs
  • Nonaddicting analgesics

ASJC Scopus subject areas

  • Chemistry(all)
  • Pharmaceutical Science
  • Pharmacology

Cite this

Development of delta opioid peptides as nonaddicting analgesics. / Rapaka, R. S.; Porreca, Frank.

In: Pharmaceutical Research, Vol. 8, No. 1, 1991, p. 1-8.

Research output: Contribution to journalArticle

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