Diagnosis and treatment of Amanita phalloides type mushroom poisoning: use of thioctic acid

C. E. Becker, T. G. Tong, U. Boerner, R. L. Roe, A. T. ScoTT, M. B. MacQuarrie, F. Bartter

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

The number of cases of mushroom poisoning is increasing as a result of the increasing popularity of 'wild' mushroom consumption. Amanitin and phalloidin cytotoxins found in some Amanita and Galerina species produce the most severe and frequent life threatening symptoms of Amanita phalloidestype poisoning. Delay in onset of symptoms, individual susceptibility variation and lack of rapid and reliable identification have contributed to the significant morbidity and mortality of this type of poisoning. A rapid chromatographic assay for identifying the potent cytotoxins and apparently successful management using thioctic acid of two cases of A. phalloides type mushroom poisoning are reported. All known cases of A. phalloides type mushroom poisoning treated with thioctic acid in the United States are summarized.

Original languageEnglish (US)
Pages (from-to)100-109
Number of pages10
JournalWestern Journal of Medicine
Volume125
Issue number2
StatePublished - Dec 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Becker, C. E., Tong, T. G., Boerner, U., Roe, R. L., ScoTT, A. T., MacQuarrie, M. B., & Bartter, F. (1976). Diagnosis and treatment of Amanita phalloides type mushroom poisoning: use of thioctic acid. Western Journal of Medicine, 125(2), 100-109.