Diagnosis and treatment of pulmonary metastases from cervical carcinoma

James F. Barter, Seng Jaw Soong, Kenneth D. Hatch, James W. Orr, Hugh M. Shingleton

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

The records of 2116 patients treated for cervical malignancy from 1969 to 1984 at the University of Alabama at Birmingham were reviewed and 88 (4.16%) had pulmonary lesions consistent with metastatic cervical cancer. The data were analyzed to characterize risk factors for developing lung metastases, to determine radiographie patterns, to assess methods of documentation, and to determine response to chemotherapy. Platinum-type chemotherapy has a 67.7% response rate on chest X ray, with one-third of the responses being complete. The prognosis is poor with a median survival of 0.69 year (8.3 months); only 2 of these 88 patients were long-term survivors. Although the survival is poor, a few statistically significant factors could be identified as prognostic. Our data do not support use of surveillance chest X rays, as there is no statistically significant survival difference in symptomatic versus asymptomatic patients. The development of more effective salvage therapy may alter this recommendation.

Original languageEnglish (US)
Pages (from-to)347-351
Number of pages5
JournalGynecologic oncology
Volume38
Issue number3
DOIs
StatePublished - Sep 1990
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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