Dinoflagellate genome evolution

Jennifer H. Wisecaver, Jeremiah D. Hackett

Research output: Contribution to journalArticle

90 Scopus citations

Abstract

The dinoflagellates are an ecologically important group of microbial eukaryotes that have evolved many novel genomic characteristics. They possess some of the largest nuclear genomes among eukaryotes arranged on permanently condensed liquid-crystalline chromosomes. Recent advances have revealed the presence of genes arranged in tandem arrays, trans-splicing of messenger RNAs, and a reduced role for transcriptional regulation compared to other eukaryotes. In contrast, the mitochondrial and plastid genomes have the smallest gene content among functional eukaryotic organelles. Dinoflagellate biology and genome evolution have been dramatically influenced by lateral transfer of individual genes and large-scale transfer of genes through endosymbiosis. Next-generation sequencing technologies have only recently made genome-scale analyses of these organisms possible, and these new methods are helping researchers better understand the biology and evolution of this enigmatic group of eukaryotes.

Original languageEnglish (US)
Pages (from-to)369-387
Number of pages19
JournalAnnual review of microbiology
Volume65
DOIs
StatePublished - Oct 3 2011

Keywords

  • Alveolate
  • Endosymbiosis
  • Gene expression
  • Gene transfer
  • trans-splicing

ASJC Scopus subject areas

  • Microbiology

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