Direct current dielectrophoretic characterization of erythrocytes: Positive ABO blood types

S. S. Keshavamurthy, K. M. Leonard, S. C. Burgess, A. M. Minerick

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

The adaptation of medical diagnostic applications into micrototal analytical systems (μTAS) has the potential to improve the ease, accessibility and rapidity of medical diagnostics. This work adapts direct current dielectrophoresis (DC-DEP) to a medical diagnostic application of sorting blood cells where an insulating obstacle is used to produce a non-uniform electric field. Initial efforts are focused on achieving separation of positive ABO red blood cells. Two dependencies will simultaneously be explored: blood type and blood cell size. Fluorescent polystyrene particles of three different sizes will be tested and compared against the separation and collection of actual blood cells into different sample bins. Further, continuous separation of red blood cells according to blood types and collection into specific bins will be explored. This developed technique is directly applicable for use in a portable device for easy and rapid blood diagnostics.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages401-404
Number of pages4
StatePublished - Oct 1 2008
Externally publishedYes
Event2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States
Duration: Jun 1 2008Jun 5 2008

Publication series

NameTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Volume3

Other

Other2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
CountryUnited States
CityQuebec City, QC
Period6/1/086/5/08

Keywords

  • ABO blood type
  • Antigens
  • Direct current dielectrophoresis (DC-DEP)
  • Microdevice
  • Red blood cells

ASJC Scopus subject areas

  • Mechanical Engineering

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  • Cite this

    Keshavamurthy, S. S., Leonard, K. M., Burgess, S. C., & Minerick, A. M. (2008). Direct current dielectrophoretic characterization of erythrocytes: Positive ABO blood types. In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (pp. 401-404). (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 3).