Disease ecology in the Galápagos Hawk (Buteo galapagoensis): Host genetic diversity, parasite load and natural antibodies

Noah K Whiteman, Kevin D. Matson, Jennifer L. Bollmer, Patricia G. Parker

Research output: Contribution to journalArticle

130 Citations (Scopus)

Abstract

An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Galápagos endemic bird, providing the context for a natural experiment examining the effects of inbreeding on disease susceptibility. Extremely inbred populations of Galápagos hawks had higher parasite abundances than relatively outbred populations. We found a significant island effect on constitutively produced natural antibody (NAb) levels and inbred populations generally harboured lower average and less variable NAb levels than relatively outbred populations. Furthermore, NAb levels explained abundance of amblyceran lice, which encounter the host immune system. This is the first study linking inbreeding, innate immunity and parasite load in an endemic, in situ wildlife population and provides a clear framework for assessment of disease risk in a Galápagos endemic.

Original languageEnglish (US)
Pages (from-to)797-804
Number of pages8
JournalProceedings of the Royal Society B: Biological Sciences
Volume273
Issue number1588
DOIs
StatePublished - Apr 7 2006
Externally publishedYes

Fingerprint

Hawks
Parasite Load
parasite intensity
Buteo
parasite load
hawks
Ecology
inbreeding
Inbreeding
antibody
ecology
genetic variation
antibodies
Islands
Antibodies
Population
Disease Susceptibility
disease resistance
wildlife
louse

Keywords

  • Disease
  • Galápagos Islands
  • Genetic diversity
  • Immune function
  • Natural antibodies

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Disease ecology in the Galápagos Hawk (Buteo galapagoensis) : Host genetic diversity, parasite load and natural antibodies. / Whiteman, Noah K; Matson, Kevin D.; Bollmer, Jennifer L.; Parker, Patricia G.

In: Proceedings of the Royal Society B: Biological Sciences, Vol. 273, No. 1588, 07.04.2006, p. 797-804.

Research output: Contribution to journalArticle

@article{c68e47bf1b6c41139bcc95cb8f35a9c6,
title = "Disease ecology in the Gal{\'a}pagos Hawk (Buteo galapagoensis): Host genetic diversity, parasite load and natural antibodies",
abstract = "An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Gal{\'a}pagos endemic bird, providing the context for a natural experiment examining the effects of inbreeding on disease susceptibility. Extremely inbred populations of Gal{\'a}pagos hawks had higher parasite abundances than relatively outbred populations. We found a significant island effect on constitutively produced natural antibody (NAb) levels and inbred populations generally harboured lower average and less variable NAb levels than relatively outbred populations. Furthermore, NAb levels explained abundance of amblyceran lice, which encounter the host immune system. This is the first study linking inbreeding, innate immunity and parasite load in an endemic, in situ wildlife population and provides a clear framework for assessment of disease risk in a Gal{\'a}pagos endemic.",
keywords = "Disease, Gal{\'a}pagos Islands, Genetic diversity, Immune function, Natural antibodies",
author = "Whiteman, {Noah K} and Matson, {Kevin D.} and Bollmer, {Jennifer L.} and Parker, {Patricia G.}",
year = "2006",
month = "4",
day = "7",
doi = "10.1098/rspb.2005.3396",
language = "English (US)",
volume = "273",
pages = "797--804",
journal = "Philosophical transactions of the Royal Society of London. Series B: Biological sciences",
issn = "0962-8436",
publisher = "Royal Society of London",
number = "1588",

}

TY - JOUR

T1 - Disease ecology in the Galápagos Hawk (Buteo galapagoensis)

T2 - Host genetic diversity, parasite load and natural antibodies

AU - Whiteman, Noah K

AU - Matson, Kevin D.

AU - Bollmer, Jennifer L.

AU - Parker, Patricia G.

PY - 2006/4/7

Y1 - 2006/4/7

N2 - An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Galápagos endemic bird, providing the context for a natural experiment examining the effects of inbreeding on disease susceptibility. Extremely inbred populations of Galápagos hawks had higher parasite abundances than relatively outbred populations. We found a significant island effect on constitutively produced natural antibody (NAb) levels and inbred populations generally harboured lower average and less variable NAb levels than relatively outbred populations. Furthermore, NAb levels explained abundance of amblyceran lice, which encounter the host immune system. This is the first study linking inbreeding, innate immunity and parasite load in an endemic, in situ wildlife population and provides a clear framework for assessment of disease risk in a Galápagos endemic.

AB - An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Galápagos endemic bird, providing the context for a natural experiment examining the effects of inbreeding on disease susceptibility. Extremely inbred populations of Galápagos hawks had higher parasite abundances than relatively outbred populations. We found a significant island effect on constitutively produced natural antibody (NAb) levels and inbred populations generally harboured lower average and less variable NAb levels than relatively outbred populations. Furthermore, NAb levels explained abundance of amblyceran lice, which encounter the host immune system. This is the first study linking inbreeding, innate immunity and parasite load in an endemic, in situ wildlife population and provides a clear framework for assessment of disease risk in a Galápagos endemic.

KW - Disease

KW - Galápagos Islands

KW - Genetic diversity

KW - Immune function

KW - Natural antibodies

UR - http://www.scopus.com/inward/record.url?scp=34249051996&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249051996&partnerID=8YFLogxK

U2 - 10.1098/rspb.2005.3396

DO - 10.1098/rspb.2005.3396

M3 - Article

C2 - 16618672

AN - SCOPUS:34249051996

VL - 273

SP - 797

EP - 804

JO - Philosophical transactions of the Royal Society of London. Series B: Biological sciences

JF - Philosophical transactions of the Royal Society of London. Series B: Biological sciences

SN - 0962-8436

IS - 1588

ER -