Disparities in incidence of early- and late-onset colorectal cancer between Hispanics and Whites: A 10-year SEER database study

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7 Citations (Scopus)

Abstract

Background: Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012. Methods: We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases. Results: The overall incidence of CRC increased by 48% in Hispanics. 38% increase in incidence of LO CRC and 80% increase in incidence of EO CRC was seen in this ethnic group. Hispanics and Whites showed higher percentage of distant tumors for both age groups. There was no deviation in overall trend between males and females. Conclusions: Although there is an overall decrease in incidence of CRC in Whites increase was seen in Hispanics. While incidence of EO CRC is increasing in both races, LO CRC incidence is increasing in Hispanics not in Whites. This data suggest that disparities in incidence of EO and LO CRC exist between Hispanics and Whites.

Original languageEnglish (US)
JournalAmerican Journal of Surgery
DOIs
StateAccepted/In press - Jan 18 2017
Externally publishedYes

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antineoplaston A10
Hispanic Americans
Colorectal Neoplasms
Databases
Incidence
Ethnic Groups
Neoplasms
Age Groups
Mortality

Keywords

  • Colorectal cancer (CRC)
  • Early-onset CRC
  • Gender
  • Hispanics
  • Incidence
  • Late-onset CRC
  • Stage of disease
  • Whites

ASJC Scopus subject areas

  • Surgery

Cite this

@article{88164aa8712c411688698f2b5e3c1091,
title = "Disparities in incidence of early- and late-onset colorectal cancer between Hispanics and Whites: A 10-year SEER database study",
abstract = "Background: Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012. Methods: We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases. Results: The overall incidence of CRC increased by 48{\%} in Hispanics. 38{\%} increase in incidence of LO CRC and 80{\%} increase in incidence of EO CRC was seen in this ethnic group. Hispanics and Whites showed higher percentage of distant tumors for both age groups. There was no deviation in overall trend between males and females. Conclusions: Although there is an overall decrease in incidence of CRC in Whites increase was seen in Hispanics. While incidence of EO CRC is increasing in both races, LO CRC incidence is increasing in Hispanics not in Whites. This data suggest that disparities in incidence of EO and LO CRC exist between Hispanics and Whites.",
keywords = "Colorectal cancer (CRC), Early-onset CRC, Gender, Hispanics, Incidence, Late-onset CRC, Stage of disease, Whites",
author = "Jenna Koblinski and Jana Jandova and Nfonsam, {Valentine N}",
year = "2017",
month = "1",
day = "18",
doi = "10.1016/j.amjsurg.2017.03.035",
language = "English (US)",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Disparities in incidence of early- and late-onset colorectal cancer between Hispanics and Whites

T2 - A 10-year SEER database study

AU - Koblinski, Jenna

AU - Jandova, Jana

AU - Nfonsam, Valentine N

PY - 2017/1/18

Y1 - 2017/1/18

N2 - Background: Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012. Methods: We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases. Results: The overall incidence of CRC increased by 48% in Hispanics. 38% increase in incidence of LO CRC and 80% increase in incidence of EO CRC was seen in this ethnic group. Hispanics and Whites showed higher percentage of distant tumors for both age groups. There was no deviation in overall trend between males and females. Conclusions: Although there is an overall decrease in incidence of CRC in Whites increase was seen in Hispanics. While incidence of EO CRC is increasing in both races, LO CRC incidence is increasing in Hispanics not in Whites. This data suggest that disparities in incidence of EO and LO CRC exist between Hispanics and Whites.

AB - Background: Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012. Methods: We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases. Results: The overall incidence of CRC increased by 48% in Hispanics. 38% increase in incidence of LO CRC and 80% increase in incidence of EO CRC was seen in this ethnic group. Hispanics and Whites showed higher percentage of distant tumors for both age groups. There was no deviation in overall trend between males and females. Conclusions: Although there is an overall decrease in incidence of CRC in Whites increase was seen in Hispanics. While incidence of EO CRC is increasing in both races, LO CRC incidence is increasing in Hispanics not in Whites. This data suggest that disparities in incidence of EO and LO CRC exist between Hispanics and Whites.

KW - Colorectal cancer (CRC)

KW - Early-onset CRC

KW - Gender

KW - Hispanics

KW - Incidence

KW - Late-onset CRC

KW - Stage of disease

KW - Whites

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