Distal administration of very high doses of intracoronary adenosine for the treatment of resistant no-reflow

Mohammad R Movahed, Gurpreet Baweja

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

No-reflow is a serious condition, and is associated with substantial morbidity and mortality after percutaneous coronary intervention. The most feared complication of no-reflow is a case of no-reflow that is resistant to multiple drug therapy. This condition usually occurs in patients with distal coronary disease or high thrombus burden. In the present case, a patient with resistant no-reflow that could be reversed by distat intracoronary administration of very high doses of adenosine (1 mg) is described. Administration of very high doses of adenosine via a balloon catheter was safe and did not cause any changes in the heart rate or blood pressure. The present case is the first to be reported in the literature.

Original languageEnglish (US)
Pages (from-to)141-146
Number of pages6
JournalExperimental and Clinical Cardiology
Volume13
Issue number3
StatePublished - 2008

Fingerprint

Adenosine
Percutaneous Coronary Intervention
Coronary Disease
Thrombosis
Catheters
Heart Rate
Blood Pressure
Morbidity
Drug Therapy
Mortality
Therapeutics

Keywords

  • Adenosine
  • Balloon angioplasty
  • Complications
  • No-reflow
  • Percutaneous coronary intervention
  • PTCA
  • Stenting

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Physiology

Cite this

Distal administration of very high doses of intracoronary adenosine for the treatment of resistant no-reflow. / Movahed, Mohammad R; Baweja, Gurpreet.

In: Experimental and Clinical Cardiology, Vol. 13, No. 3, 2008, p. 141-146.

Research output: Contribution to journalArticle

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