Distinctive intestinal mast cell neoplasms of domestic cats

J. Alroy, I. Leav, R. A. DeLellis, Ronald S Weinstein

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

By means of histologic, histochemical, and ultrastructural techniques a group of distinctive intestinal neoplasms of domestic cats, previously thought to arise from enterochromaffin cells, were redefined as mast cell neoplasms. Although these tumors differed histologically from the more typical visceral mast cell neoplasm of cats, ultrastructural and histochemical similarities between cells comprising both tumors were encountered. Differences in granule morphology and histochemical characteristics were, however, consistently demonstrated when the neoplasms were compared. The intestinal neoplasms are not associated with ulceration of the gastrointestinal tract unlike many mast cell tumors involving viscera. The authors suggest that the differences between the cells in the typical visceral and intestinal tumors confirm and extend the concept of the existence of morphologic and functionally heterogeneous populations of mast cells occurring in different anatomical locations of the body.

Original languageEnglish (US)
Pages (from-to)159-167
Number of pages9
JournalLaboratory Investigation
Volume33
Issue number2
StatePublished - 1975
Externally publishedYes

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Mast Cells
Cats
Neoplasms
Intestinal Neoplasms
Enterochromaffin Cells
Viscera
Gastrointestinal Tract
Population

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Distinctive intestinal mast cell neoplasms of domestic cats. / Alroy, J.; Leav, I.; DeLellis, R. A.; Weinstein, Ronald S.

In: Laboratory Investigation, Vol. 33, No. 2, 1975, p. 159-167.

Research output: Contribution to journalArticle

Alroy, J, Leav, I, DeLellis, RA & Weinstein, RS 1975, 'Distinctive intestinal mast cell neoplasms of domestic cats', Laboratory Investigation, vol. 33, no. 2, pp. 159-167.
Alroy, J. ; Leav, I. ; DeLellis, R. A. ; Weinstein, Ronald S. / Distinctive intestinal mast cell neoplasms of domestic cats. In: Laboratory Investigation. 1975 ; Vol. 33, No. 2. pp. 159-167.
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