Disturbed expression of ribonucleotide reductase and cytokeratin polypeptides in focal epithelial hyperplasia. An immunohistochemical study using monoclonal antibodies.

B. Rozell, G. Stenman, B. Magnusson, U. Lekholm, Raymond B Nagle, H. A. Hansson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Four cases of focal epithelial hyperplasia (FEH) were studied immunohistochemically, using monoclonal antibodies against the M1 subunit of ribonucleotide reductase and different cytokeratin polypeptides. The FEH lesions showed, compared to normal oral mucosa, extensive alterations in their staining patterns. This included ectopic suprabasal M1 staining and the novel expression of cytokeratin polypeptides differing from those previously reported for other HPV infections. The results are discussed in relation to the causative agent, human papillomavirus, and its expression in focal epithelial hyperplasia.

Original languageEnglish (US)
Pages (from-to)261-264
Number of pages4
JournalJournal of Oral Pathology
Volume15
Issue number5
StatePublished - May 1986

Fingerprint

Focal Epithelial Hyperplasia
Ribonucleotide Reductases
Keratins
Monoclonal Antibodies
Peptides
Staining and Labeling
Mouth Mucosa
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Disturbed expression of ribonucleotide reductase and cytokeratin polypeptides in focal epithelial hyperplasia. An immunohistochemical study using monoclonal antibodies. / Rozell, B.; Stenman, G.; Magnusson, B.; Lekholm, U.; Nagle, Raymond B; Hansson, H. A.

In: Journal of Oral Pathology, Vol. 15, No. 5, 05.1986, p. 261-264.

Research output: Contribution to journalArticle

@article{fe3f494db95a40cb833681af880f7e20,
title = "Disturbed expression of ribonucleotide reductase and cytokeratin polypeptides in focal epithelial hyperplasia. An immunohistochemical study using monoclonal antibodies.",
abstract = "Four cases of focal epithelial hyperplasia (FEH) were studied immunohistochemically, using monoclonal antibodies against the M1 subunit of ribonucleotide reductase and different cytokeratin polypeptides. The FEH lesions showed, compared to normal oral mucosa, extensive alterations in their staining patterns. This included ectopic suprabasal M1 staining and the novel expression of cytokeratin polypeptides differing from those previously reported for other HPV infections. The results are discussed in relation to the causative agent, human papillomavirus, and its expression in focal epithelial hyperplasia.",
author = "B. Rozell and G. Stenman and B. Magnusson and U. Lekholm and Nagle, {Raymond B} and Hansson, {H. A.}",
year = "1986",
month = "5",
language = "English (US)",
volume = "15",
pages = "261--264",
journal = "Journal of Oral Pathology and Medicine",
issn = "0904-2512",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Disturbed expression of ribonucleotide reductase and cytokeratin polypeptides in focal epithelial hyperplasia. An immunohistochemical study using monoclonal antibodies.

AU - Rozell, B.

AU - Stenman, G.

AU - Magnusson, B.

AU - Lekholm, U.

AU - Nagle, Raymond B

AU - Hansson, H. A.

PY - 1986/5

Y1 - 1986/5

N2 - Four cases of focal epithelial hyperplasia (FEH) were studied immunohistochemically, using monoclonal antibodies against the M1 subunit of ribonucleotide reductase and different cytokeratin polypeptides. The FEH lesions showed, compared to normal oral mucosa, extensive alterations in their staining patterns. This included ectopic suprabasal M1 staining and the novel expression of cytokeratin polypeptides differing from those previously reported for other HPV infections. The results are discussed in relation to the causative agent, human papillomavirus, and its expression in focal epithelial hyperplasia.

AB - Four cases of focal epithelial hyperplasia (FEH) were studied immunohistochemically, using monoclonal antibodies against the M1 subunit of ribonucleotide reductase and different cytokeratin polypeptides. The FEH lesions showed, compared to normal oral mucosa, extensive alterations in their staining patterns. This included ectopic suprabasal M1 staining and the novel expression of cytokeratin polypeptides differing from those previously reported for other HPV infections. The results are discussed in relation to the causative agent, human papillomavirus, and its expression in focal epithelial hyperplasia.

UR - http://www.scopus.com/inward/record.url?scp=0022708935&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022708935&partnerID=8YFLogxK

M3 - Article

C2 - 2427675

AN - SCOPUS:0022708935

VL - 15

SP - 261

EP - 264

JO - Journal of Oral Pathology and Medicine

JF - Journal of Oral Pathology and Medicine

SN - 0904-2512

IS - 5

ER -