Do patients with HIV-associated minor cognitive/motor disorder exhibit a “subcortical” memory profile? evidence using the california verbal learning test

Dean C. Delis, Guerry Peavy, Robert Heaton, Nelson Butters, David P. Salmon, Michael Taylor, Julie Stout, Parag Mehta, T Lee Ryan, Desiree White, J. Hampton Atkinson, James L. Chandler, J. Allen McCutchan, Igor Grant, Hnrc Group

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

A new diagnostic category for HIV seropositive patients–Minor Cognitive/Motor Disorder (MCMD)—was recently proposed by an AIDS task force sponsored by the American Academy of Neurology. Based on past memory research with HIV+ patients who were diagnosed according to the Center for Disease Control (CDC) definition of AIDS, we predicted that HIV+ patients who met the new criteria for MCMD would exhibit a “subcortical” memory profile (i.e., they would display primarily a retrieval deficit). This hypothesis was generally supported, but with some exceptions. The HIV+ patients with MCMD were found to have a mild encoding deficit (suggestive of some cortical involvement) superimposed on a pronounced retrieval deficit (suggestive of more extensive subcortical involvement). These findings are consonant with those from a recent neuropathological study indicating an increase in cortical involvement, in addition to predominately subcortical involvement, in more advance stages of the HIV disease process.

Original languageEnglish (US)
Pages (from-to)151-165
Number of pages15
JournalAssessment
Volume2
Issue number2
DOIs
StatePublished - 1995
Externally publishedYes

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Verbal Learning
HIV
Acquired Immunodeficiency Syndrome
Advisory Committees
Centers for Disease Control and Prevention (U.S.)
Motor Disorders
Research

ASJC Scopus subject areas

  • Clinical Psychology
  • Applied Psychology

Cite this

Do patients with HIV-associated minor cognitive/motor disorder exhibit a “subcortical” memory profile? evidence using the california verbal learning test. / Delis, Dean C.; Peavy, Guerry; Heaton, Robert; Butters, Nelson; Salmon, David P.; Taylor, Michael; Stout, Julie; Mehta, Parag; Ryan, T Lee; White, Desiree; Atkinson, J. Hampton; Chandler, James L.; McCutchan, J. Allen; Grant, Igor; Group, Hnrc.

In: Assessment, Vol. 2, No. 2, 1995, p. 151-165.

Research output: Contribution to journalArticle

Delis, DC, Peavy, G, Heaton, R, Butters, N, Salmon, DP, Taylor, M, Stout, J, Mehta, P, Ryan, TL, White, D, Atkinson, JH, Chandler, JL, McCutchan, JA, Grant, I & Group, H 1995, 'Do patients with HIV-associated minor cognitive/motor disorder exhibit a “subcortical” memory profile? evidence using the california verbal learning test', Assessment, vol. 2, no. 2, pp. 151-165. https://doi.org/10.1177/107319119500200205
Delis, Dean C. ; Peavy, Guerry ; Heaton, Robert ; Butters, Nelson ; Salmon, David P. ; Taylor, Michael ; Stout, Julie ; Mehta, Parag ; Ryan, T Lee ; White, Desiree ; Atkinson, J. Hampton ; Chandler, James L. ; McCutchan, J. Allen ; Grant, Igor ; Group, Hnrc. / Do patients with HIV-associated minor cognitive/motor disorder exhibit a “subcortical” memory profile? evidence using the california verbal learning test. In: Assessment. 1995 ; Vol. 2, No. 2. pp. 151-165.
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