Does epigenetics play a role in human asthma?

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Asthma and other allergic diseases are among the most prevalent chronic non-communicable diseases of childhood. According to the World Health Organization, asthma affects >7.0 million children under 18 in the United States, with an economic burden that is estimated to exceed that of tuberculosis and HIV/AIDS combined. Despite much research, the natural history of asthma and its pathogenesis are still in many ways elusive. This review discusses our current understanding of the role epigenetic processes play in asthma pathogenesis, focusing on genome-wide, population-based studies.

Original languageEnglish (US)
Pages (from-to)123-126
Number of pages4
JournalAllergology International
Volume65
Issue number2
DOIs
StatePublished - Apr 1 2016

Keywords

  • Allergy
  • Birth cohort
  • Childhood asthma
  • DNA methylation
  • Epigenetics

ASJC Scopus subject areas

  • Immunology and Allergy

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