Dose verification for accelerated partial breast irradiation

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Noticeable advances have been made in reducing the reoccurrence of breast cancer after a lumpectomy through invasive irradiation of the surrounding participating tissue. One effective postoperative procedure introduces a radionuclide applicator surrounded by an inflatable balloon into the evacuated breast cavity. Through, a series of polyethylene guide tubes, radioactive sources are introduced in a time-controlled program to irradiate tissue surrounding the lumpectomy site to a desired integrated dose of about 30 Gy at a depth of 1cm over a 5-day period in 10 treatment fractions. To be most effective and to minimize collateral radiation damage, reliable and accurate dose estimates must be performed in the patient treatment planning stage. The current treatment uses the TG-43 protocol [1] where radiation transport is estimated in a standard tissue phantom to provide best estimates of the delivered dose. Given today's computational power and comprehensive radiation transport algorithms, it is generally thought by those in the radiation oncology community that we should be able to more precisely predict doses, which is the subject of this presentation.

Original languageEnglish (US)
Title of host publicationAmerican Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009
Pages1371-1381
Number of pages11
Volume2
StatePublished - 2009
EventInternational Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009 - Saratoga Springs, NY, United States
Duration: May 3 2009May 7 2009

Other

OtherInternational Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009
CountryUnited States
CitySaratoga Springs, NY
Period5/3/095/7/09

Fingerprint

breast
Irradiation
Dosimetry
Dose
Tissue
Partial
Radiation
dosage
irradiation
radiation transport
Patient treatment
Applicators
Oncology
Balloons
Radiation damage
Radiation Damage
Radioisotopes
Balloon
Polyethylenes
balloons

Keywords

  • APRI
  • Brachytherapy
  • HDR
  • Ir-192

ASJC Scopus subject areas

  • Nuclear Energy and Engineering
  • Computational Mathematics
  • Nuclear and High Energy Physics

Cite this

Hadad, K., Ganapol, B. D., Hamilton, R. J., & Watchman, C. J. (2009). Dose verification for accelerated partial breast irradiation. In American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009 (Vol. 2, pp. 1371-1381)

Dose verification for accelerated partial breast irradiation. / Hadad, Kamal; Ganapol, Barry D; Hamilton, Russell J; Watchman, Christopher J.

American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009. Vol. 2 2009. p. 1371-1381.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hadad, K, Ganapol, BD, Hamilton, RJ & Watchman, CJ 2009, Dose verification for accelerated partial breast irradiation. in American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009. vol. 2, pp. 1371-1381, International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009, Saratoga Springs, NY, United States, 5/3/09.
Hadad K, Ganapol BD, Hamilton RJ, Watchman CJ. Dose verification for accelerated partial breast irradiation. In American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009. Vol. 2. 2009. p. 1371-1381
Hadad, Kamal ; Ganapol, Barry D ; Hamilton, Russell J ; Watchman, Christopher J. / Dose verification for accelerated partial breast irradiation. American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009. Vol. 2 2009. pp. 1371-1381
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