Dose verification for accelerated partial breast irradiation

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Noticeable advances have been made in reducing the reoccurrence of breast cancer after a lumpectomy through invasive irradiation of the surrounding participating tissue. One effective postoperative procedure introduces a radionuclide applicator surrounded by an inflatable balloon into the evacuated breast cavity. Through, a series of polyethylene guide tubes, radioactive sources are introduced in a time-controlled program to irradiate tissue surrounding the lumpectomy site to a desired integrated dose of about 30 Gy at a depth of 1cm over a 5-day period in 10 treatment fractions. To be most effective and to minimize collateral radiation damage, reliable and accurate dose estimates must be performed in the patient treatment planning stage. The current treatment uses the TG-43 protocol [1] where radiation transport is estimated in a standard tissue phantom to provide best estimates of the delivered dose. Given today's computational power and comprehensive radiation transport algorithms, it is generally thought by those in the radiation oncology community that we should be able to more precisely predict doses, which is the subject of this presentation.

Original languageEnglish (US)
Title of host publicationAmerican Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009
Pages1371-1381
Number of pages11
StatePublished - Dec 1 2009
EventInternational Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009 - Saratoga Springs, NY, United States
Duration: May 3 2009May 7 2009

Publication series

NameAmerican Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009
Volume2

Other

OtherInternational Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009
CountryUnited States
CitySaratoga Springs, NY
Period5/3/095/7/09

Keywords

  • APRI
  • Brachytherapy
  • HDR
  • Ir-192

ASJC Scopus subject areas

  • Nuclear Energy and Engineering
  • Computational Mathematics
  • Nuclear and High Energy Physics

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    Hadad, K., Ganapol, B. D., Hamilton, R., & Watchman, C. (2009). Dose verification for accelerated partial breast irradiation. In American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009 (pp. 1371-1381). (American Nuclear Society - International Conference on Mathematics, Computational Methods and Reactor Physics 2009, M and C 2009; Vol. 2).