Dual-detector probe for surgical tumor staging

T. S. Hickernell, H. B. Barber, Harrison H Barrett, J. M. Woolfenden

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

A hand-held, dual-detector probe has been developed for surgical tumor staging. This dual probe simultaneously monitors counts from a possible tumor site along with counts from adjacent normal tissue using two concentric, collimated scintillation detectors. A comparison of counts from the detectors can distinguish a small tumor directly in front of the probe from variations in background activity. The probe was tested in computer simulations of surgical staging of metastases to para-aortic and iliac lymph nodes using a spatial response map of the probe, a numerical torso phantom, and organ activity data for [57Co]bleomycin in rabbits. Results show that the dual probe performs better than a single-detector probe in detecting tumors and solves the problem caused by spatial variations in the background source distribution.

Original languageEnglish (US)
Pages (from-to)1101-1106
Number of pages6
JournalJournal of Nuclear Medicine
Volume29
Issue number6
StatePublished - 1988

Fingerprint

Neoplasm Staging
Torso
Neoplasms
Computer Simulation
Hand
Lymph Nodes
Neoplasm Metastasis
Rabbits

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Hickernell, T. S., Barber, H. B., Barrett, H. H., & Woolfenden, J. M. (1988). Dual-detector probe for surgical tumor staging. Journal of Nuclear Medicine, 29(6), 1101-1106.

Dual-detector probe for surgical tumor staging. / Hickernell, T. S.; Barber, H. B.; Barrett, Harrison H; Woolfenden, J. M.

In: Journal of Nuclear Medicine, Vol. 29, No. 6, 1988, p. 1101-1106.

Research output: Contribution to journalArticle

Hickernell, TS, Barber, HB, Barrett, HH & Woolfenden, JM 1988, 'Dual-detector probe for surgical tumor staging', Journal of Nuclear Medicine, vol. 29, no. 6, pp. 1101-1106.
Hickernell TS, Barber HB, Barrett HH, Woolfenden JM. Dual-detector probe for surgical tumor staging. Journal of Nuclear Medicine. 1988;29(6):1101-1106.
Hickernell, T. S. ; Barber, H. B. ; Barrett, Harrison H ; Woolfenden, J. M. / Dual-detector probe for surgical tumor staging. In: Journal of Nuclear Medicine. 1988 ; Vol. 29, No. 6. pp. 1101-1106.
@article{73c8bf578b2f4991a129d4cb740cf037,
title = "Dual-detector probe for surgical tumor staging",
abstract = "A hand-held, dual-detector probe has been developed for surgical tumor staging. This dual probe simultaneously monitors counts from a possible tumor site along with counts from adjacent normal tissue using two concentric, collimated scintillation detectors. A comparison of counts from the detectors can distinguish a small tumor directly in front of the probe from variations in background activity. The probe was tested in computer simulations of surgical staging of metastases to para-aortic and iliac lymph nodes using a spatial response map of the probe, a numerical torso phantom, and organ activity data for [57Co]bleomycin in rabbits. Results show that the dual probe performs better than a single-detector probe in detecting tumors and solves the problem caused by spatial variations in the background source distribution.",
author = "Hickernell, {T. S.} and Barber, {H. B.} and Barrett, {Harrison H} and Woolfenden, {J. M.}",
year = "1988",
language = "English (US)",
volume = "29",
pages = "1101--1106",
journal = "Journal of Nuclear Medicine",
issn = "0161-5505",
publisher = "Society of Nuclear Medicine Inc.",
number = "6",

}

TY - JOUR

T1 - Dual-detector probe for surgical tumor staging

AU - Hickernell, T. S.

AU - Barber, H. B.

AU - Barrett, Harrison H

AU - Woolfenden, J. M.

PY - 1988

Y1 - 1988

N2 - A hand-held, dual-detector probe has been developed for surgical tumor staging. This dual probe simultaneously monitors counts from a possible tumor site along with counts from adjacent normal tissue using two concentric, collimated scintillation detectors. A comparison of counts from the detectors can distinguish a small tumor directly in front of the probe from variations in background activity. The probe was tested in computer simulations of surgical staging of metastases to para-aortic and iliac lymph nodes using a spatial response map of the probe, a numerical torso phantom, and organ activity data for [57Co]bleomycin in rabbits. Results show that the dual probe performs better than a single-detector probe in detecting tumors and solves the problem caused by spatial variations in the background source distribution.

AB - A hand-held, dual-detector probe has been developed for surgical tumor staging. This dual probe simultaneously monitors counts from a possible tumor site along with counts from adjacent normal tissue using two concentric, collimated scintillation detectors. A comparison of counts from the detectors can distinguish a small tumor directly in front of the probe from variations in background activity. The probe was tested in computer simulations of surgical staging of metastases to para-aortic and iliac lymph nodes using a spatial response map of the probe, a numerical torso phantom, and organ activity data for [57Co]bleomycin in rabbits. Results show that the dual probe performs better than a single-detector probe in detecting tumors and solves the problem caused by spatial variations in the background source distribution.

UR - http://www.scopus.com/inward/record.url?scp=0023936953&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023936953&partnerID=8YFLogxK

M3 - Article

C2 - 3373318

AN - SCOPUS:0023936953

VL - 29

SP - 1101

EP - 1106

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

SN - 0161-5505

IS - 6

ER -