Dual-detector probe for surgical tumor staging

T. S. Hickernell, H. B. Barber, H. H. Barrett, J. M. Woolfenden

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

A hand-held, dual-detector probe has been developed for surgical tumor staging. This dual probe simultaneously monitors counts from a possible tumor site along with counts from adjacent normal tissue using two concentric, collimated scintillation detectors. A comparison of counts from the detectors can distinguish a small tumor directly in front of the probe from variations in background activity. The probe was tested in computer simulations of surgical staging of metastases to para-aortic and iliac lymph nodes using a spatial response map of the probe, a numerical torso phantom, and organ activity data for [57Co]bleomycin in rabbits. Results show that the dual probe performs better than a single-detector probe in detecting tumors and solves the problem caused by spatial variations in the background source distribution.

Original languageEnglish (US)
Pages (from-to)1101-1106
Number of pages6
JournalJournal of Nuclear Medicine
Volume29
Issue number6
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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