Dynamic mechanical characterization of poly(glycerol sebacate)/poly(butylene succinate-butylene dilinoleate) blends for cardiac tissue engineering by flat punch nanoindentation

B. Merle, X. Kraus, M. Tallawi, B. Scharfe, M. El Fray, K. E. Aifantis, A. R. Boccaccini, M. Göken

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine.

Original languageEnglish (US)
Pages (from-to)115-118
Number of pages4
JournalMaterials Letters
Volume221
DOIs
StatePublished - Jun 15 2018

Keywords

  • Cardiac tissue engineering
  • Dynamic mechanical analysis
  • Nanoindentation

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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