Dynamic mechanical characterization of poly(glycerol sebacate)/poly(butylene succinate-butylene dilinoleate) blends for cardiac tissue engineering by flat punch nanoindentation

B. Merle, X. Kraus, M. Tallawi, B. Scharfe, M. El Fray, Katerina E Aifantis, A. R. Boccaccini, M. Göken

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine.

Original languageEnglish (US)
Pages (from-to)115-118
Number of pages4
JournalMaterials Letters
Volume221
DOIs
StatePublished - Jun 15 2018
Externally publishedYes

Keywords

  • Cardiac tissue engineering
  • Dynamic mechanical analysis
  • Nanoindentation

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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