Eating in, eating out

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

For a Kafkaesque tale of murder and mayhem, of matricide and insecticide, of pathogenesis and mutualism, and yes, of friendship and cooperation, we now turn our attention to Photorhabdus luminescens. But, be warned: this is not a tale for the weak-hearted! P. luminescens, a close relative of the Yersiniae, are gram-negative bacteria that reside peacefully within the gut of the nematode, Heterorhabditis spp1. The free-living form of this nematode is found in the soil as a non-feeding and long-lived 'infective juvenile' (IJ). The IJ actively seeks out any of a number of insect larvae within which it will complete the rest of its life cycle. Once a victim is found, the nematode penetrates into the blood stream of the unfortunate larva and regurgitates its bacterial partner. L-proline, the most abundant amino acid in insect blood, signals the bacteria to turn on an array of virulence genes, and also serves as its preferred energy source2. These genes are involved in adherence, colonization and subversion of the insect innate immune system. P. luminescens also encodes the greatest number of putative toxins compared to any other sequenced bacterial genome.

Original languageEnglish (US)
Pages (from-to)207-208
Number of pages2
JournalGut Microbes
Volume1
Issue number4
DOIs
StatePublished - 2010

Fingerprint

Photorhabdus
Insects
Eating
Larva
Bacterial Genomes
Yersinia
Symbiosis
Homicide
Insecticides
Life Cycle Stages
Gram-Negative Bacteria
Proline
Genes
Virulence
Immune System
Soil
Bacteria
Amino Acids

Keywords

  • Heterorhabditis
  • Hotorhabdus luminescens
  • Mutualism
  • Pathogenesis
  • Symbiosis

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology

Cite this

Eating in, eating out. / Viswanathan, Virinchipuram.

In: Gut Microbes, Vol. 1, No. 4, 2010, p. 207-208.

Research output: Contribution to journalArticle

Viswanathan, Virinchipuram. / Eating in, eating out. In: Gut Microbes. 2010 ; Vol. 1, No. 4. pp. 207-208.
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