Echinoclasterol sulfate phenethylammonium salt, a unique steroid sulfate from the marine sponge, Echinoclathria subhispida

Hong yu Li, Shigeki Matsunaga, Nobuhiro Fusetani, Hirota Fujiki, Peter T. Murphy, Richard H. Willis, Joseph T. Baker

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

A phenethylammonium salt of a new steroid sulfate, echinoclasterol sulfate (1) has been isolated from the marine sponge, Echinoclathria subhispida. The structure was determined by interpretation of spectral data including 2D NMR and FABMS. It exhibited antifungal activity against Mortierella ramannianus, and cytotoxicity against PC-9 human lung cancer cells.

Original languageEnglish (US)
Pages (from-to)5733-5736
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number36
DOIs
StatePublished - Sep 3 1993

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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