High frequency jet ventilation (HFJV) is becoming increasingly useful for providing respiratory support in patients with normal lungs during operative procedures,, and also has been advocated as a technique for ventilating patients during cardiopulmonary resuscitation. We studied the effect of frequency, percent inspiratory time ( I E ratio), peak airway pressure, and airway pressure difference (peak-PEEP) during HFJV as operational variables on the efficacy of gas exchange in dogs with normal lungs. We observed that at a constant peak airway pressure and. percent inspiratory time, PaCo2 generally increases as frequency rises above 100/min. In constrast, PaC02 generally decreases as percent inspiratory time is reduced at a constant frequency and peak airway pressure. In addition, increasing peak airway pressure and airway pressure difference are associated with lower levels of PaCo2. Arterial oxygenation was adversely affected by frequencies above 300/min, but was otherwise not influenced by alterations in frequency, percent inspiratory time, or airway pressure.
- Gas exchange
- High frequency jet ventilation
- Operational guidelines
- Operational variables
ASJC Scopus subject areas
- Emergency Medicine
- Cardiology and Cardiovascular Medicine