Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging

Russell S Witte, Kang Kim, Bernard J. Martin, Matthew O'Donnell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Citations (Scopus)

Abstract

The etiology of skeletal muscle fatigue is not well understood partly because techniques portraying muscle performance in vivo are limited by either their invasiveness (e.g., needle electrodes) or poor spatial resolution (e.g., surface EMG). To better characterize effects of FES and muscle fatigue, we captured real-time high resolution dynamics of the human forearm before and after a fatigue exercise using ultrasound strain imaging. A 10 MHz linear ultrasound probe aligned with the fiber axis of the 3rd flexor digitorum superficialis (FDS) provided scans at 3-msec intervals during isometric twitch and tetanic contractions evoked by low and high frequency electrical stimuli (ES). Ultrasound images synchronized with traditional force and EMG were obtained for 5 healthy adults before and after a fatiguing exercise, induced by sustained maximal exertion of the middle finger pressed against a restraint until the initial force decreased by 75% Immediately after fatigue, twitch and tetanic stimuli generated 55.1% and 19.5% less force, respectively, implying that low frequency fatigue dominated. The force deficit was associated with a decrease in several mechanical properties of the fatigued muscle during twitch contractions, such as transverse peak strain (34±15%) and half peak strain duration (32.3±12.5 msec). Changes were not uniform across the imaged section of the muscle, suggesting that boundary conditions or fiber heterogeneity affected the strain profile. Indeed, high stress zones appeared closer to the muscle-tendon junction during isometric contractions. This study provided new insight on the elastic behavior of muscle and potential mechanisms of injury, especially directed at prolonged stimulation and control of a neuromuscular prosthesis.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages4490-4493
Number of pages4
DOIs
StatePublished - 2006
Externally publishedYes
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

Fingerprint

Muscle
Elasticity
Ultrasonics
Fatigue of materials
Imaging techniques
Fibers
Tendons
Needles
Boundary conditions
Mechanical properties
Electrodes

ASJC Scopus subject areas

  • Bioengineering

Cite this

Witte, R. S., Kim, K., Martin, B. J., & O'Donnell, M. (2006). Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 4490-4493). [4030452] https://doi.org/10.1109/IEMBS.2006.260850

Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging. / Witte, Russell S; Kim, Kang; Martin, Bernard J.; O'Donnell, Matthew.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 4490-4493 4030452.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Witte, RS, Kim, K, Martin, BJ & O'Donnell, M 2006, Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4030452, pp. 4490-4493, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06, New York, NY, United States, 8/30/06. https://doi.org/10.1109/IEMBS.2006.260850
Witte RS, Kim K, Martin BJ, O'Donnell M. Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 4490-4493. 4030452 https://doi.org/10.1109/IEMBS.2006.260850
Witte, Russell S ; Kim, Kang ; Martin, Bernard J. ; O'Donnell, Matthew. / Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. pp. 4490-4493
@inproceedings{e7bc036878e649a09afb653c83bc948c,
title = "Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging",
abstract = "The etiology of skeletal muscle fatigue is not well understood partly because techniques portraying muscle performance in vivo are limited by either their invasiveness (e.g., needle electrodes) or poor spatial resolution (e.g., surface EMG). To better characterize effects of FES and muscle fatigue, we captured real-time high resolution dynamics of the human forearm before and after a fatigue exercise using ultrasound strain imaging. A 10 MHz linear ultrasound probe aligned with the fiber axis of the 3rd flexor digitorum superficialis (FDS) provided scans at 3-msec intervals during isometric twitch and tetanic contractions evoked by low and high frequency electrical stimuli (ES). Ultrasound images synchronized with traditional force and EMG were obtained for 5 healthy adults before and after a fatiguing exercise, induced by sustained maximal exertion of the middle finger pressed against a restraint until the initial force decreased by 75{\%} Immediately after fatigue, twitch and tetanic stimuli generated 55.1{\%} and 19.5{\%} less force, respectively, implying that low frequency fatigue dominated. The force deficit was associated with a decrease in several mechanical properties of the fatigued muscle during twitch contractions, such as transverse peak strain (34±15{\%}) and half peak strain duration (32.3±12.5 msec). Changes were not uniform across the imaged section of the muscle, suggesting that boundary conditions or fiber heterogeneity affected the strain profile. Indeed, high stress zones appeared closer to the muscle-tendon junction during isometric contractions. This study provided new insight on the elastic behavior of muscle and potential mechanisms of injury, especially directed at prolonged stimulation and control of a neuromuscular prosthesis.",
author = "Witte, {Russell S} and Kang Kim and Martin, {Bernard J.} and Matthew O'Donnell",
year = "2006",
doi = "10.1109/IEMBS.2006.260850",
language = "English (US)",
isbn = "1424400325",
pages = "4490--4493",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

}

TY - GEN

T1 - Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging

AU - Witte, Russell S

AU - Kim, Kang

AU - Martin, Bernard J.

AU - O'Donnell, Matthew

PY - 2006

Y1 - 2006

N2 - The etiology of skeletal muscle fatigue is not well understood partly because techniques portraying muscle performance in vivo are limited by either their invasiveness (e.g., needle electrodes) or poor spatial resolution (e.g., surface EMG). To better characterize effects of FES and muscle fatigue, we captured real-time high resolution dynamics of the human forearm before and after a fatigue exercise using ultrasound strain imaging. A 10 MHz linear ultrasound probe aligned with the fiber axis of the 3rd flexor digitorum superficialis (FDS) provided scans at 3-msec intervals during isometric twitch and tetanic contractions evoked by low and high frequency electrical stimuli (ES). Ultrasound images synchronized with traditional force and EMG were obtained for 5 healthy adults before and after a fatiguing exercise, induced by sustained maximal exertion of the middle finger pressed against a restraint until the initial force decreased by 75% Immediately after fatigue, twitch and tetanic stimuli generated 55.1% and 19.5% less force, respectively, implying that low frequency fatigue dominated. The force deficit was associated with a decrease in several mechanical properties of the fatigued muscle during twitch contractions, such as transverse peak strain (34±15%) and half peak strain duration (32.3±12.5 msec). Changes were not uniform across the imaged section of the muscle, suggesting that boundary conditions or fiber heterogeneity affected the strain profile. Indeed, high stress zones appeared closer to the muscle-tendon junction during isometric contractions. This study provided new insight on the elastic behavior of muscle and potential mechanisms of injury, especially directed at prolonged stimulation and control of a neuromuscular prosthesis.

AB - The etiology of skeletal muscle fatigue is not well understood partly because techniques portraying muscle performance in vivo are limited by either their invasiveness (e.g., needle electrodes) or poor spatial resolution (e.g., surface EMG). To better characterize effects of FES and muscle fatigue, we captured real-time high resolution dynamics of the human forearm before and after a fatigue exercise using ultrasound strain imaging. A 10 MHz linear ultrasound probe aligned with the fiber axis of the 3rd flexor digitorum superficialis (FDS) provided scans at 3-msec intervals during isometric twitch and tetanic contractions evoked by low and high frequency electrical stimuli (ES). Ultrasound images synchronized with traditional force and EMG were obtained for 5 healthy adults before and after a fatiguing exercise, induced by sustained maximal exertion of the middle finger pressed against a restraint until the initial force decreased by 75% Immediately after fatigue, twitch and tetanic stimuli generated 55.1% and 19.5% less force, respectively, implying that low frequency fatigue dominated. The force deficit was associated with a decrease in several mechanical properties of the fatigued muscle during twitch contractions, such as transverse peak strain (34±15%) and half peak strain duration (32.3±12.5 msec). Changes were not uniform across the imaged section of the muscle, suggesting that boundary conditions or fiber heterogeneity affected the strain profile. Indeed, high stress zones appeared closer to the muscle-tendon junction during isometric contractions. This study provided new insight on the elastic behavior of muscle and potential mechanisms of injury, especially directed at prolonged stimulation and control of a neuromuscular prosthesis.

UR - http://www.scopus.com/inward/record.url?scp=34047123740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34047123740&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2006.260850

DO - 10.1109/IEMBS.2006.260850

M3 - Conference contribution

C2 - 17947090

AN - SCOPUS:34047123740

SN - 1424400325

SN - 9781424400324

SP - 4490

EP - 4493

BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ER -