Effect of multiple light paths on retinal vessel oximetry

Matthew H. Smith, Kurt R Denninghoff, Arthur Lompado, Lloyd W. Hillman

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.

Original languageEnglish (US)
Pages (from-to)1183-1193
Number of pages11
JournalApplied Optics
Volume39
Issue number7
StatePublished - Mar 1 2000
Externally publishedYes

Fingerprint

Oximeters
oximetry
vessels
Blood
Backscattering
Cells
erythrocytes
arteries
Scanning
veins
blood
Oxygen
Geometry
backscattering
saturation
scanning
oxygen
geometry

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Smith, M. H., Denninghoff, K. R., Lompado, A., & Hillman, L. W. (2000). Effect of multiple light paths on retinal vessel oximetry. Applied Optics, 39(7), 1183-1193.

Effect of multiple light paths on retinal vessel oximetry. / Smith, Matthew H.; Denninghoff, Kurt R; Lompado, Arthur; Hillman, Lloyd W.

In: Applied Optics, Vol. 39, No. 7, 01.03.2000, p. 1183-1193.

Research output: Contribution to journalArticle

Smith, MH, Denninghoff, KR, Lompado, A & Hillman, LW 2000, 'Effect of multiple light paths on retinal vessel oximetry', Applied Optics, vol. 39, no. 7, pp. 1183-1193.
Smith MH, Denninghoff KR, Lompado A, Hillman LW. Effect of multiple light paths on retinal vessel oximetry. Applied Optics. 2000 Mar 1;39(7):1183-1193.
Smith, Matthew H. ; Denninghoff, Kurt R ; Lompado, Arthur ; Hillman, Lloyd W. / Effect of multiple light paths on retinal vessel oximetry. In: Applied Optics. 2000 ; Vol. 39, No. 7. pp. 1183-1193.
@article{fcbfe69cc2c6496ea3ba090454f7fdcb,
title = "Effect of multiple light paths on retinal vessel oximetry",
abstract = "Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.",
author = "Smith, {Matthew H.} and Denninghoff, {Kurt R} and Arthur Lompado and Hillman, {Lloyd W.}",
year = "2000",
month = "3",
day = "1",
language = "English (US)",
volume = "39",
pages = "1183--1193",
journal = "Applied Optics",
issn = "1559-128X",
publisher = "The Optical Society",
number = "7",

}

TY - JOUR

T1 - Effect of multiple light paths on retinal vessel oximetry

AU - Smith, Matthew H.

AU - Denninghoff, Kurt R

AU - Lompado, Arthur

AU - Hillman, Lloyd W.

PY - 2000/3/1

Y1 - 2000/3/1

N2 - Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.

AB - Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.

UR - http://www.scopus.com/inward/record.url?scp=0000256333&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0000256333&partnerID=8YFLogxK

M3 - Article

C2 - 18338002

AN - SCOPUS:0000256333

VL - 39

SP - 1183

EP - 1193

JO - Applied Optics

JF - Applied Optics

SN - 1559-128X

IS - 7

ER -