Effect of Reserpine on Serum Prolactin, Growth Hormone, and Glucocorticoids in Dairy Cows

D. E. Bauman, R. J. Collier, H. A. Tucker

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Nonlactating, nonpregnant Holstein cows were used to examine the effects of an im injection of reserpine. A 5-mg reserpine injection resulted in a rapid (within 0.5 hr) and sustained (at least 24 hr) elevation of serum prolactin. Peak prolactin levels (283 ng/ml) occurred 3 hr postinjection. Serum glucocorticoid and growth hormone concentrations were unaffected by reserpine injection. Two sequential injections of 5 mg of reserpine given at 48-hr intervals gave nearly identical prolactin responses. The prolactin response to reserpine was dose dependent with 1 mg giving approximately 39.5% of the response obtained with 5 mg of reserpine.

Original languageEnglish (US)
Pages (from-to)189-192
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume155
Issue number2
DOIs
StatePublished - Jun 1977

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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