Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.
|Original language||English (US)|
|Number of pages||7|
|Journal||Nutrition and Cancer|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science