Effects of Chronic β-Carotene Supplementation on Vitamin K Status in Adult

Louise M. Canfield, James J. Corrigan, J. Jeter, Patricia M. Plezia, Susan Sayers, David S. Alberts

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily ft-carotene supplementation (0,15,30, ruuor 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic 0-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of (3-carotene and vitamin K. (Nutr Cancer 13, 263–269, 1990).

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalNutrition and cancer
Issue number4
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Oncology
  • Nutrition and Dietetics
  • Cancer Research


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