Abstract
Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 263-269 |
| Number of pages | 7 |
| Journal | Nutrition and Cancer |
| Volume | 13 |
| Issue number | 4 |
| State | Published - 1990 |
Fingerprint
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Oncology
- Food Science
Cite this
Effects of chronic β-carotene supplementation on vitamin K status in adults. / Canfield, L. M.; Corrigan, J. J.; Plezia, P. M.; Jeter, M.; Sayers, S.; Alberts, David S.
In: Nutrition and Cancer, Vol. 13, No. 4, 1990, p. 263-269.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of chronic β-carotene supplementation on vitamin K status in adults
AU - Canfield, L. M.
AU - Corrigan, J. J.
AU - Plezia, P. M.
AU - Jeter, M.
AU - Sayers, S.
AU - Alberts, David S
PY - 1990
Y1 - 1990
N2 - Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.
AB - Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.
UR - http://www.scopus.com/inward/record.url?scp=0025330058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025330058&partnerID=8YFLogxK
M3 - Article
C2 - 2189123
AN - SCOPUS:0025330058
VL - 13
SP - 263
EP - 269
JO - Nutrition and Cancer
JF - Nutrition and Cancer
SN - 0163-5581
IS - 4
ER -