Abstract
Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 263-269 |
| Number of pages | 7 |
| Journal | Nutrition and Cancer |
| Volume | 13 |
| Issue number | 4 |
| Publication status | Published - 1990 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Oncology
- Food Science
Cite this
Canfield, L. M., Corrigan, J. J., Plezia, P. M., Jeter, M., Sayers, S., & Alberts, D. S. (1990). Effects of chronic β-carotene supplementation on vitamin K status in adults. Nutrition and Cancer, 13(4), 263-269.