Effects of chronic β-carotene supplementation on vitamin K status in adults

L. M. Canfield, J. J. Corrigan, P. M. Plezia, M. Jeter, S. Sayers, David S Alberts

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily β-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic β-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of β-carotene and vitamin K.

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalNutrition and Cancer
Volume13
Issue number4
StatePublished - 1990

Fingerprint

vitamin K
Vitamin K
Carotenoids
carotenes
long term effects
coagulation
vitamin K deficiency
Vitamin K Deficiency
prothrombin
intestinal absorption
Intestinal Absorption
Prothrombin
dosage

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Oncology
  • Food Science

Cite this

Canfield, L. M., Corrigan, J. J., Plezia, P. M., Jeter, M., Sayers, S., & Alberts, D. S. (1990). Effects of chronic β-carotene supplementation on vitamin K status in adults. Nutrition and Cancer, 13(4), 263-269.

Effects of chronic β-carotene supplementation on vitamin K status in adults. / Canfield, L. M.; Corrigan, J. J.; Plezia, P. M.; Jeter, M.; Sayers, S.; Alberts, David S.

In: Nutrition and Cancer, Vol. 13, No. 4, 1990, p. 263-269.

Research output: Contribution to journalArticle

Canfield, LM, Corrigan, JJ, Plezia, PM, Jeter, M, Sayers, S & Alberts, DS 1990, 'Effects of chronic β-carotene supplementation on vitamin K status in adults', Nutrition and Cancer, vol. 13, no. 4, pp. 263-269.
Canfield LM, Corrigan JJ, Plezia PM, Jeter M, Sayers S, Alberts DS. Effects of chronic β-carotene supplementation on vitamin K status in adults. Nutrition and Cancer. 1990;13(4):263-269.
Canfield, L. M. ; Corrigan, J. J. ; Plezia, P. M. ; Jeter, M. ; Sayers, S. ; Alberts, David S. / Effects of chronic β-carotene supplementation on vitamin K status in adults. In: Nutrition and Cancer. 1990 ; Vol. 13, No. 4. pp. 263-269.
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