Effects of physicochemical properties of nanomaterials on their toxicity

Xiaoming Li, Wei Liu, Lianwen Sun, Katerina E Aifantis, Bo Yu, Yubo Fan, Qingling Feng, Fuzhai Cui, Fumio Watari

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Abstract Due to their unique size and properties, nanomaterials have numerous applications, which range from electronics, cosmetics, household appliances, energy storage, and semiconductor devices, to medical products such as biological sensors, drug carriers, bioprobes, and implants. Many of the promising properties of nanomaterials arise from their large surface to volume ratio and, therefore, nanobiomaterials that are implantable have a large contact area with the human body. Before, therefore, we can fully exploit nanomaterials, in medicine and bioengineering; it is necessary to understand how they can affect the human body. As a step in this direction, this review paper provides a comprehensive summary of the effects that the physicochemical properties of commonly used nanobiomaterials have on their toxicity. Furthermore, the possible mechanisms of toxicity are described with the aim to provide guidance concerning the design of the nanobiomaterials with desirable properties.

Original languageEnglish (US)
Pages (from-to)2499-2507
Number of pages9
JournalJournal of Biomedical Materials Research - Part A
Volume103
Issue number7
DOIs
StatePublished - Jul 1 2015

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Nanostructured materials
Toxicity
Drug Implants
Domestic appliances
Drug Carriers
Cosmetics
Semiconductor devices
Energy storage
Medicine
Electronic equipment
Sensors

Keywords

  • nanomaterials
  • nanoparticles
  • physicochemical properties
  • toxicity

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Ceramics and Composites
  • Metals and Alloys

Cite this

Effects of physicochemical properties of nanomaterials on their toxicity. / Li, Xiaoming; Liu, Wei; Sun, Lianwen; Aifantis, Katerina E; Yu, Bo; Fan, Yubo; Feng, Qingling; Cui, Fuzhai; Watari, Fumio.

In: Journal of Biomedical Materials Research - Part A, Vol. 103, No. 7, 01.07.2015, p. 2499-2507.

Research output: Contribution to journalArticle

Li, Xiaoming ; Liu, Wei ; Sun, Lianwen ; Aifantis, Katerina E ; Yu, Bo ; Fan, Yubo ; Feng, Qingling ; Cui, Fuzhai ; Watari, Fumio. / Effects of physicochemical properties of nanomaterials on their toxicity. In: Journal of Biomedical Materials Research - Part A. 2015 ; Vol. 103, No. 7. pp. 2499-2507.
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AU - Feng, Qingling

AU - Cui, Fuzhai

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