Effects of resistance training on regional and total bone mineral density in premenopausal women

A randomized prospective study

Timothy G Lohman, Scott B Going, Richard Pamenter, Matthew Hall, Thomas Boyden, Linda Houtkooper, Linda K Houtkooper, Lisa Bare, Anabel Hill, Mikel Aickin

Research output: Contribution to journalArticle

224 Citations (Scopus)

Abstract

This study was designed to assess the effects of 18 months of resistance exercise on regional and total bone mineral density (BMD) and soft tissue lean mass (STL) in premenopausal women aged 28-39 randomly assigned to an exercise or control group. Twenty-two exercise and 34 control subjects completed the 18-month training study. All subjects were previously inactive and untrained women. Initial, 5-, 12- and 18-month assessments were made of total and regional BMD and total and regional STL using dual energy X-ray absorptiometry. All subjects consumed a 500 mg/day elemental calcium supplement throughout the study. Initial Ca intake without supplement averaged 1,023 mg/day in total sample. Serum levels of bone osteocalcin and dietary assessments using 12 randomly assigned days of diet records were also completed. Muscular strength was assessed from both 1 repetition maximum (RM) testing of 10 weightlifting exercises and by peak torque for hip abduction/adduction and knee extension/flexion. Training increased strength by 58.1% based on 1 RM testing and by 33.8% based on isokinetic testing at 18 months versus baseline. BMD increased significantly above baseline at the lumbar spine for the exercise group at 5 months (2.8%), 12 months (2.3%), and 18 months (1.9%) as compared with controls. Femur trochanter BMD increased significantly (p < 0.05) in the exercise group at 12 months (1.8%) and 18 months (2.0%) but not at 5 months (0.7%) as compared with controls. No changes in total BMD, arm BMD, or leg BMD were found. There was a 20% increase in BGP in the exercise group as compared with controls at 5 months and this difference was maintained throughout the study. For STL, significant increases for total, arm, and leg were found at 5, 12, and 18 months for the exercise group versus control ranging from 1-6% over baseline. These results support the use of strength training for increasing STL and muscular strength with smaller but significant regional increases in BMD in the premenopausal population.

Original languageEnglish (US)
Pages (from-to)1015-1024
Number of pages10
JournalJournal of Bone and Mineral Research
Volume10
Issue number7
StatePublished - Jul 1995

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Resistance Training
Bone Density
Prospective Studies
Exercise
Leg Bones
Femur
Arm Bones
Diet Records
Control Groups
Osteocalcin
Photon Absorptiometry
Torque
Hip
Leg
Knee
Spine
Arm
Calcium
Bone and Bones
Serum

ASJC Scopus subject areas

  • Surgery

Cite this

Effects of resistance training on regional and total bone mineral density in premenopausal women : A randomized prospective study. / Lohman, Timothy G; Going, Scott B; Pamenter, Richard; Hall, Matthew; Boyden, Thomas; Houtkooper, Linda; Houtkooper, Linda K; Bare, Lisa; Hill, Anabel; Aickin, Mikel.

In: Journal of Bone and Mineral Research, Vol. 10, No. 7, 07.1995, p. 1015-1024.

Research output: Contribution to journalArticle

Lohman, Timothy G ; Going, Scott B ; Pamenter, Richard ; Hall, Matthew ; Boyden, Thomas ; Houtkooper, Linda ; Houtkooper, Linda K ; Bare, Lisa ; Hill, Anabel ; Aickin, Mikel. / Effects of resistance training on regional and total bone mineral density in premenopausal women : A randomized prospective study. In: Journal of Bone and Mineral Research. 1995 ; Vol. 10, No. 7. pp. 1015-1024.
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