Effects of respirator dead space, inspiratory resistance, and expiratory resistance ventilatory loads

Philip I Harber, S. Shimozaki, T. Barrett, P. Losides, G. Fine

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The effects of respiratorlike inspiratory resistance (IR), expiratory resistance (ER), and dead space (DS) were assessed in a group of 11 normal volunteers during moderate steady-state (SS) and rapidly incremented (RI) exercise. The physiologic effects of IR were predominant, increasing inspiratory time, duty cycle, and several measures of ventilatory work. Effects of DS appear related to increased minute ventilation and include increasing flow rates and duty cylce and requiring greater ventilatory work; during RI exercise, the DS effect became relatively smaller at higher exercise levels. ER compressed expiratory time. These results characterize the response to IR, ER, and DS loads and suggest that DS may be relatively less physiologically significant than IR.

Original languageEnglish (US)
Pages (from-to)189-198
Number of pages10
JournalAmerican Journal of Industrial Medicine
Volume16
Issue number2
StatePublished - 1989
Externally publishedYes

Fingerprint

Mechanical Ventilators
Exercise
Ventilation
Healthy Volunteers

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Effects of respirator dead space, inspiratory resistance, and expiratory resistance ventilatory loads. / Harber, Philip I; Shimozaki, S.; Barrett, T.; Losides, P.; Fine, G.

In: American Journal of Industrial Medicine, Vol. 16, No. 2, 1989, p. 189-198.

Research output: Contribution to journalArticle

@article{217319c319bf4ae3a0babaf2ea53a925,
title = "Effects of respirator dead space, inspiratory resistance, and expiratory resistance ventilatory loads",
abstract = "The effects of respiratorlike inspiratory resistance (IR), expiratory resistance (ER), and dead space (DS) were assessed in a group of 11 normal volunteers during moderate steady-state (SS) and rapidly incremented (RI) exercise. The physiologic effects of IR were predominant, increasing inspiratory time, duty cycle, and several measures of ventilatory work. Effects of DS appear related to increased minute ventilation and include increasing flow rates and duty cylce and requiring greater ventilatory work; during RI exercise, the DS effect became relatively smaller at higher exercise levels. ER compressed expiratory time. These results characterize the response to IR, ER, and DS loads and suggest that DS may be relatively less physiologically significant than IR.",
author = "Harber, {Philip I} and S. Shimozaki and T. Barrett and P. Losides and G. Fine",
year = "1989",
language = "English (US)",
volume = "16",
pages = "189--198",
journal = "American Journal of Industrial Medicine",
issn = "0271-3586",
publisher = "Wiley-Liss Inc.",
number = "2",

}

TY - JOUR

T1 - Effects of respirator dead space, inspiratory resistance, and expiratory resistance ventilatory loads

AU - Harber, Philip I

AU - Shimozaki, S.

AU - Barrett, T.

AU - Losides, P.

AU - Fine, G.

PY - 1989

Y1 - 1989

N2 - The effects of respiratorlike inspiratory resistance (IR), expiratory resistance (ER), and dead space (DS) were assessed in a group of 11 normal volunteers during moderate steady-state (SS) and rapidly incremented (RI) exercise. The physiologic effects of IR were predominant, increasing inspiratory time, duty cycle, and several measures of ventilatory work. Effects of DS appear related to increased minute ventilation and include increasing flow rates and duty cylce and requiring greater ventilatory work; during RI exercise, the DS effect became relatively smaller at higher exercise levels. ER compressed expiratory time. These results characterize the response to IR, ER, and DS loads and suggest that DS may be relatively less physiologically significant than IR.

AB - The effects of respiratorlike inspiratory resistance (IR), expiratory resistance (ER), and dead space (DS) were assessed in a group of 11 normal volunteers during moderate steady-state (SS) and rapidly incremented (RI) exercise. The physiologic effects of IR were predominant, increasing inspiratory time, duty cycle, and several measures of ventilatory work. Effects of DS appear related to increased minute ventilation and include increasing flow rates and duty cylce and requiring greater ventilatory work; during RI exercise, the DS effect became relatively smaller at higher exercise levels. ER compressed expiratory time. These results characterize the response to IR, ER, and DS loads and suggest that DS may be relatively less physiologically significant than IR.

UR - http://www.scopus.com/inward/record.url?scp=0024361018&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024361018&partnerID=8YFLogxK

M3 - Article

VL - 16

SP - 189

EP - 198

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

SN - 0271-3586

IS - 2

ER -