Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets

P. D. Whanger, P. H. Weswig, John A Schmitz, J. E. Oldfield

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

The effects of selenium and vitamin E on blood selenium levels and tissue glutathione peroxidase activities were determined in sheep fed purified and hay diets. A significant increase of blood levels of this element and tissue glutathione peroxidase activities was found in sheep given selenium as compared to those not receiving this element. Of the tissues examined, the highest glutathione peroxidase activity was found in the heart. Vitamin E had no influence on either the blood selenium levels or upon the tissue glutathione peroxidase activity. With hydrogen peroxide as the substrate, tissue glutathione peroxidase activity was not correlated with the incidence of white muscle disease. Evidence is presented to suggest that 0.1 ppm dietary selenium is not sufficient under some conditions to meet the physiological requirements for this element.

Original languageEnglish (US)
Pages (from-to)1298-1307
Number of pages10
JournalJournal of Nutrition
Volume107
Issue number7
StatePublished - 1977
Externally publishedYes

Fingerprint

White Muscle Disease
white muscle disease
Selenium
Glutathione Peroxidase
Vitamin E
glutathione peroxidase
selenium
hay
vitamin E
Sheep
Diet
sheep
blood
diet
Hydrogen Peroxide
hydrogen peroxide
heart
tissues
incidence
Incidence

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets. / Whanger, P. D.; Weswig, P. H.; Schmitz, John A; Oldfield, J. E.

In: Journal of Nutrition, Vol. 107, No. 7, 1977, p. 1298-1307.

Research output: Contribution to journalArticle

@article{e8f87ae183304f95a1cf213d57346e6e,
title = "Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets",
abstract = "The effects of selenium and vitamin E on blood selenium levels and tissue glutathione peroxidase activities were determined in sheep fed purified and hay diets. A significant increase of blood levels of this element and tissue glutathione peroxidase activities was found in sheep given selenium as compared to those not receiving this element. Of the tissues examined, the highest glutathione peroxidase activity was found in the heart. Vitamin E had no influence on either the blood selenium levels or upon the tissue glutathione peroxidase activity. With hydrogen peroxide as the substrate, tissue glutathione peroxidase activity was not correlated with the incidence of white muscle disease. Evidence is presented to suggest that 0.1 ppm dietary selenium is not sufficient under some conditions to meet the physiological requirements for this element.",
author = "Whanger, {P. D.} and Weswig, {P. H.} and Schmitz, {John A} and Oldfield, {J. E.}",
year = "1977",
language = "English (US)",
volume = "107",
pages = "1298--1307",
journal = "Journal of Nutrition",
issn = "0022-3166",
publisher = "American Society for Nutrition",
number = "7",

}

TY - JOUR

T1 - Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets

AU - Whanger, P. D.

AU - Weswig, P. H.

AU - Schmitz, John A

AU - Oldfield, J. E.

PY - 1977

Y1 - 1977

N2 - The effects of selenium and vitamin E on blood selenium levels and tissue glutathione peroxidase activities were determined in sheep fed purified and hay diets. A significant increase of blood levels of this element and tissue glutathione peroxidase activities was found in sheep given selenium as compared to those not receiving this element. Of the tissues examined, the highest glutathione peroxidase activity was found in the heart. Vitamin E had no influence on either the blood selenium levels or upon the tissue glutathione peroxidase activity. With hydrogen peroxide as the substrate, tissue glutathione peroxidase activity was not correlated with the incidence of white muscle disease. Evidence is presented to suggest that 0.1 ppm dietary selenium is not sufficient under some conditions to meet the physiological requirements for this element.

AB - The effects of selenium and vitamin E on blood selenium levels and tissue glutathione peroxidase activities were determined in sheep fed purified and hay diets. A significant increase of blood levels of this element and tissue glutathione peroxidase activities was found in sheep given selenium as compared to those not receiving this element. Of the tissues examined, the highest glutathione peroxidase activity was found in the heart. Vitamin E had no influence on either the blood selenium levels or upon the tissue glutathione peroxidase activity. With hydrogen peroxide as the substrate, tissue glutathione peroxidase activity was not correlated with the incidence of white muscle disease. Evidence is presented to suggest that 0.1 ppm dietary selenium is not sufficient under some conditions to meet the physiological requirements for this element.

UR - http://www.scopus.com/inward/record.url?scp=0017735717&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017735717&partnerID=8YFLogxK

M3 - Article

C2 - 874573

AN - SCOPUS:0017735717

VL - 107

SP - 1298

EP - 1307

JO - Journal of Nutrition

JF - Journal of Nutrition

SN - 0022-3166

IS - 7

ER -