Effects of water load on renal glomerular and tubular function in desert quail

E. J. Braun, W. H. Dantzler

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Effects of an acute intravenous water load on glomerular and tubular function were studied in the anesthetized desert quail Lophortyx gambelii. Total kidney glomerular filtration rate (GFR) and single nephron glomerular filtration rates (SNGFR) of reptilian type and mammalian type nephrons increased by more than 50% compared with the GFR and SNGFRs measured during a control mannitol diuresis. Despite the increase in GFR, urine flow rate was only 56% of that in control mannitol diuresis, free water clearance [C(H20)] remained at 1-2% of GFR, and the animals excreted only about 79% of the water load. More than 99% of the filtered sodium and 93% of the filtered water were reabsorbed during the water load. Possible reasons for the increased GFR and the failure to produce a dilute urine or excrete the water load are discussed.

Original languageEnglish (US)
Pages (from-to)222-228
Number of pages7
JournalAmerican Journal of Physiology
Volume229
Issue number1
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Physiology (medical)

Fingerprint Dive into the research topics of 'Effects of water load on renal glomerular and tubular function in desert quail'. Together they form a unique fingerprint.

  • Cite this