Efficacy of transcutaneous computed tomography-guided fine needle aspiration biopsy in patients with laryngeal squamous cell carcinoma, probable failed radiation therapy, and negative transmucosal biopsies

Martin J. Citardi, James J. Abrahams, Stuart Flynn, Clarence T. Sasaki

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

For patients with suspected recurrent/persistent laryngeal squamous cell carcinoma (SCC) after external beam radiotherapy (EBRT), routine transmucosal biopsies obtained during direct laryngoscopy may fail to reveal active carcinoma. We evaluated transcutaneous computed tomography-guided fine needle aspiration (CTGFNA) in three consecutive patients who had a persistently fixed true vocal fold after EBRT that had been administered for laryngeal SCC and who had multiple negative transmucosal laryngeal biopsies. All three CTGFNA biopsies were positive, but final pathology confirmed invasive SCC in only one of the three patients. Despite its theoretical advantages, CTGFNA in its present form requires further assessment and/or modification.

Original languageEnglish (US)
Pages (from-to)1244-1247
Number of pages4
JournalLaryngoscope
Volume106
Issue number10
DOIs
StatePublished - Oct 1996

ASJC Scopus subject areas

  • Otorhinolaryngology

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