Efficient access to 2,3-diarylimidazo[1,2-a ]pyridines via a one-pot, ligand-free, palladium-catalyzed three-component reaction under microwave irradiation

Yuanxiang Wang, Brendan Frett, Hong Yu Li

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Abstract

An expeditious one-pot, ligand-free, Pd(OAc)2-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines analogues.

Original languageEnglish (US)
Pages (from-to)3016-3019
Number of pages4
JournalOrganic Letters
Volume16
Issue number11
DOIs
StatePublished - Jun 6 2014

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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