Efficient access to 2,3-diarylimidazo[1,2-a ]pyridines via a one-pot, ligand-free, palladium-catalyzed three-component reaction under microwave irradiation

Yuanxiang Wang, Brendan Frett, Hong Yu Li

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

An expeditious one-pot, ligand-free, Pd(OAc)2-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines analogues.

Original languageEnglish (US)
Pages (from-to)3016-3019
Number of pages4
JournalOrganic Letters
Volume16
Issue number11
DOIs
StatePublished - Jun 6 2014

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Pyridines
Microwave irradiation
Palladium
Microwaves
palladium
pyridines
Ligands
microwaves
ligands
irradiation
synthesis
availability
reagents
Availability
methodology
analogs
Molecules
molecules
palladium(II) acetate

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Efficient access to 2,3-diarylimidazo[1,2-a ]pyridines via a one-pot, ligand-free, palladium-catalyzed three-component reaction under microwave irradiation. / Wang, Yuanxiang; Frett, Brendan; Li, Hong Yu.

In: Organic Letters, Vol. 16, No. 11, 06.06.2014, p. 3016-3019.

Research output: Contribution to journalArticle

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