Ehlers-Danlos syndrome, type VIII presenting with periodontitis and prolonged bleeding time

C. Cunniff, L. Williamson-Kruse

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

We report on a case of Ehlers-Danlos syndrome, probable type VIII (EDS VIII) in a 6-year-old girl with severe periodontitis, extensive bruising of the shins, abnormal bleeding time, and thin body habitus. The structure and biosynthesis of types I and III collagen were normal. Desmopressin (DDAVP) was found to correct the bleeding time, and the patient underwent an uneventful dental procedure after DDAVP therapy. The finding of childhood or juvenile periodontitis should prompt consideration of a diagnosis of EDS, particularly type VIII, and alert the clinician to the possibility of a treatable bleeding abnormality.

Original languageEnglish (US)
Pages (from-to)145-149
Number of pages5
JournalClinical Dysmorphology
Volume4
Issue number2
DOIs
StatePublished - Jan 1 1995

Keywords

  • Ehlers-Danlos syndrome
  • Periodontitis
  • Platelet dysfunction
  • Prolonged bleeding

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anatomy
  • Pathology and Forensic Medicine
  • Genetics(clinical)

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