Elevation of plasma bromide levels in patients following halothane anesthesia

Time correlation with total halothane dosage

J. H. Tinker, A Jay Gandolfi, R. A. Van Dyke

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Plasma bromide concentrations of 25 patients were determined before and after halothane anesthesia. A high correlation (r > .70) between exposure to halothane in MAC hours and plasma bromide levels 24, 48 and 72 hours later was found. Peak bromide levels occurred 48-72 hours after anesthesia in 16 patients (64 per cent), and ranged from 52 μg/ml (0.65 mEq/l) to 180 μq/ml (2.25 mEq/l). Bromide levels remained elevated for prolonged periods (at least 22 days in some patients). Possible sedative or psychoactive effects of increased plasma bromide levels are discussed.

Original languageEnglish (US)
Pages (from-to)194-196
Number of pages3
JournalAnesthesiology
Volume44
Issue number3
StatePublished - 1976
Externally publishedYes

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Halothane
Bromides
Anesthesia
Hypnotics and Sedatives

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Elevation of plasma bromide levels in patients following halothane anesthesia : Time correlation with total halothane dosage. / Tinker, J. H.; Gandolfi, A Jay; Van Dyke, R. A.

In: Anesthesiology, Vol. 44, No. 3, 1976, p. 194-196.

Research output: Contribution to journalArticle

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