Emergent percutaneous coronary intervention for resuscitated victims of out-of-hospital cardiac arrest

Karl B Kern, Ossama Rahman

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Long-term survival rates even after successful resuscitation from out-of-hospital cardiac arrest are dismal. Most of those initially resuscitated expired during their hospitalization. Recent reports have suggested that a more aggressive approach to postresuscitation care is the key to better outcome. Waiting for the evidence of neurological recovery before acting can result in missed opportunity to improve such recovery. Immediate induction of mild therapeutic hypothermia for all resuscitated victims who remain comatose offers the best hope for neurological recovery. Numerous reports suggest that early coronary angiography and PCI also improve outcome among those resuscitated from cardiac arrest whose postresuscitation ECG show evidence of ST elevation myocardial infarctions. Most promising is combining these two postresuscitation therapies, namely immediate induction of hypothermia and early coronary angiography and PCI. Combining these therapies has resulted in long-term survival rates of 70% with more than 80% of all such survivors neurologically functional. Even those without ST elevation on their postresuscitation ECG can greatly benefit from timely induction of hypothermia and early angiography/PCI.

Original languageEnglish (US)
Pages (from-to)616-624
Number of pages9
JournalCatheterization and Cardiovascular Interventions
Volume75
Issue number4
DOIs
StatePublished - Mar 1 2010

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Out-of-Hospital Cardiac Arrest
Percutaneous Coronary Intervention
Hypothermia
Coronary Angiography
Hope
Electrocardiography
Survival Rate
Induced Hypothermia
Coma
Heart Arrest
Resuscitation
Survivors
Angiography
Hospitalization
Therapeutics
ST Elevation Myocardial Infarction

Keywords

  • Cardiopulmonary resuscitation
  • Postresuscitation care
  • Therapeutic hypothermia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Emergent percutaneous coronary intervention for resuscitated victims of out-of-hospital cardiac arrest. / Kern, Karl B; Rahman, Ossama.

In: Catheterization and Cardiovascular Interventions, Vol. 75, No. 4, 01.03.2010, p. 616-624.

Research output: Contribution to journalArticle

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