Enantiomerically Pure Acetals in Organic Synthesis. 1. Chromatographic Separability of Furanoside and Pyranoside Acetals Derived from α-Hydroxy Esters

Eugene A. Mash, Jeffrey B. Arterburn, James A. Fryling, Susan H. Mitchell

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

A general chromatographic separation of diastereomeric furanoside and pyranoside acetals derived from α-hydroxy esters is described. Application of this separation methodology is made to rapid syntheses of the diastereomers of (S)-methyl lactyl 4-deoxy-β-erythro-pentopyranoside.

Original languageEnglish (US)
Pages (from-to)1088-1093
Number of pages6
JournalJournal of Organic Chemistry
Volume56
Issue number3
DOIs
StatePublished - Feb 1 1991

ASJC Scopus subject areas

  • Organic Chemistry

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