Endocytosis in different lifestyles of protozoan parasitism: Role in nutrient uptake with special reference to Toxoplasma gondii

Bruno Robibaro, Heinrich C. Hoppe, Mei Yang, Isabelle Coppens, Huân M. Ngô, Timothy T. Stedman, Kerstin Paprotka, Keith A Joiner

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A fundamental property of any eukaryotic cell is endocytosis, that is the ability to take up external fluid, solutes and particulate matter into membrane-bound intracellular vesicles by various mechanisms. Toxoplasma gondii is an intracellular protozoan parasite of the phylum Apicomplexa with a wide geographical and host range distribution. Significant progress in studying the cell biology of this parasite has been accomplished over the last few years. Only recently endocytic compartments and endocytic trafficking have come to a closer dissection in T. gondii. In this review, we discuss the evidence for an endocytic compartment and present a model for an endocytic pathway in Toxoplasma against a background of endocytosis in kinetoplastida and the extensive insights gained from mammalian and yeast cells.

Original languageEnglish (US)
Pages (from-to)1343-1353
Number of pages11
JournalInternational Journal for Parasitology
Volume31
Issue number12
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Toxoplasma
Endocytosis
Life Style
Parasites
Kinetoplastida
Apicomplexa
Intracellular Membranes
Aptitude
Particulate Matter
Host Specificity
Eukaryotic Cells
Cell Biology
Dissection
Yeasts

Keywords

  • Apicomplexa
  • Endocytosis
  • Kinetoplastida
  • Membrane trafficking
  • Nutrient acquisition
  • Protozoa
  • Rab proteins

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Endocytosis in different lifestyles of protozoan parasitism : Role in nutrient uptake with special reference to Toxoplasma gondii. / Robibaro, Bruno; Hoppe, Heinrich C.; Yang, Mei; Coppens, Isabelle; Ngô, Huân M.; Stedman, Timothy T.; Paprotka, Kerstin; Joiner, Keith A.

In: International Journal for Parasitology, Vol. 31, No. 12, 2001, p. 1343-1353.

Research output: Contribution to journalArticle

Robibaro, Bruno ; Hoppe, Heinrich C. ; Yang, Mei ; Coppens, Isabelle ; Ngô, Huân M. ; Stedman, Timothy T. ; Paprotka, Kerstin ; Joiner, Keith A. / Endocytosis in different lifestyles of protozoan parasitism : Role in nutrient uptake with special reference to Toxoplasma gondii. In: International Journal for Parasitology. 2001 ; Vol. 31, No. 12. pp. 1343-1353.
@article{6b26cc26e4894b42ab1b92389bfaa58f,
title = "Endocytosis in different lifestyles of protozoan parasitism: Role in nutrient uptake with special reference to Toxoplasma gondii",
abstract = "A fundamental property of any eukaryotic cell is endocytosis, that is the ability to take up external fluid, solutes and particulate matter into membrane-bound intracellular vesicles by various mechanisms. Toxoplasma gondii is an intracellular protozoan parasite of the phylum Apicomplexa with a wide geographical and host range distribution. Significant progress in studying the cell biology of this parasite has been accomplished over the last few years. Only recently endocytic compartments and endocytic trafficking have come to a closer dissection in T. gondii. In this review, we discuss the evidence for an endocytic compartment and present a model for an endocytic pathway in Toxoplasma against a background of endocytosis in kinetoplastida and the extensive insights gained from mammalian and yeast cells.",
keywords = "Apicomplexa, Endocytosis, Kinetoplastida, Membrane trafficking, Nutrient acquisition, Protozoa, Rab proteins",
author = "Bruno Robibaro and Hoppe, {Heinrich C.} and Mei Yang and Isabelle Coppens and Ng{\^o}, {Hu{\^a}n M.} and Stedman, {Timothy T.} and Kerstin Paprotka and Joiner, {Keith A}",
year = "2001",
doi = "10.1016/S0020-7519(01)00252-1",
language = "English (US)",
volume = "31",
pages = "1343--1353",
journal = "International Journal for Parasitology",
issn = "0020-7519",
publisher = "Elsevier Limited",
number = "12",

}

TY - JOUR

T1 - Endocytosis in different lifestyles of protozoan parasitism

T2 - Role in nutrient uptake with special reference to Toxoplasma gondii

AU - Robibaro, Bruno

AU - Hoppe, Heinrich C.

AU - Yang, Mei

AU - Coppens, Isabelle

AU - Ngô, Huân M.

AU - Stedman, Timothy T.

AU - Paprotka, Kerstin

AU - Joiner, Keith A

PY - 2001

Y1 - 2001

N2 - A fundamental property of any eukaryotic cell is endocytosis, that is the ability to take up external fluid, solutes and particulate matter into membrane-bound intracellular vesicles by various mechanisms. Toxoplasma gondii is an intracellular protozoan parasite of the phylum Apicomplexa with a wide geographical and host range distribution. Significant progress in studying the cell biology of this parasite has been accomplished over the last few years. Only recently endocytic compartments and endocytic trafficking have come to a closer dissection in T. gondii. In this review, we discuss the evidence for an endocytic compartment and present a model for an endocytic pathway in Toxoplasma against a background of endocytosis in kinetoplastida and the extensive insights gained from mammalian and yeast cells.

AB - A fundamental property of any eukaryotic cell is endocytosis, that is the ability to take up external fluid, solutes and particulate matter into membrane-bound intracellular vesicles by various mechanisms. Toxoplasma gondii is an intracellular protozoan parasite of the phylum Apicomplexa with a wide geographical and host range distribution. Significant progress in studying the cell biology of this parasite has been accomplished over the last few years. Only recently endocytic compartments and endocytic trafficking have come to a closer dissection in T. gondii. In this review, we discuss the evidence for an endocytic compartment and present a model for an endocytic pathway in Toxoplasma against a background of endocytosis in kinetoplastida and the extensive insights gained from mammalian and yeast cells.

KW - Apicomplexa

KW - Endocytosis

KW - Kinetoplastida

KW - Membrane trafficking

KW - Nutrient acquisition

KW - Protozoa

KW - Rab proteins

UR - http://www.scopus.com/inward/record.url?scp=0034825044&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034825044&partnerID=8YFLogxK

U2 - 10.1016/S0020-7519(01)00252-1

DO - 10.1016/S0020-7519(01)00252-1

M3 - Article

C2 - 11566302

AN - SCOPUS:0034825044

VL - 31

SP - 1343

EP - 1353

JO - International Journal for Parasitology

JF - International Journal for Parasitology

SN - 0020-7519

IS - 12

ER -