Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution

Andrew D W Geering, Florian Maumus, Dario Copetti, Nathalie Choisne, Derrick J. Zwickl, Matthias Zytnicki, Alistair R. McTaggart, Simone Scalabrin, Silvia Vezzulli, Rod A Wing, Hadi Quesneville, Pierre Yves Teycheney

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The extent and importance of endogenous viral elements have been extensively described in animals but are much less well understood in plants. Here we describe a new genus of Caulimoviridae called € Florendovirus €, members of which have colonized the genomes of a large diversity of flowering plants, sometimes at very high copy numbers (>0.5% total genome content). The genome invasion of Oryza is dated to over 1.8 million years ago (MYA) but phylogeographic evidence points to an even older age of 20-34 MYA for this virus group. Some appear to have had a bipartite genome organization, a unique characteristic among viral retroelements. In Vitis vinifera, 9% of the endogenous florendovirus loci are located within introns and therefore may influence host gene expression. The frequent colocation of endogenous florendovirus loci with TA simple sequence repeats, which are associated with chromosome fragility, suggests sequence capture during repair of double-stranded DNA breaks.

Original languageEnglish (US)
Article number5269
JournalNature Communications
Volume5
DOIs
StatePublished - 2014

Fingerprint

Plant Genome
genome
viruses
Viruses
Genes
Genome
loci
Caulimoviridae
Chromosome Fragility
Retroelements
Double-Stranded DNA Breaks
gene expression
chromosomes
Vitis
Chromosomes
Gene expression
Microsatellite Repeats
Introns
animals
Animals

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)
  • Physics and Astronomy(all)

Cite this

Geering, A. D. W., Maumus, F., Copetti, D., Choisne, N., Zwickl, D. J., Zytnicki, M., ... Teycheney, P. Y. (2014). Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution. Nature Communications, 5, [5269]. https://doi.org/10.1038/ncomms6269

Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution. / Geering, Andrew D W; Maumus, Florian; Copetti, Dario; Choisne, Nathalie; Zwickl, Derrick J.; Zytnicki, Matthias; McTaggart, Alistair R.; Scalabrin, Simone; Vezzulli, Silvia; Wing, Rod A; Quesneville, Hadi; Teycheney, Pierre Yves.

In: Nature Communications, Vol. 5, 5269, 2014.

Research output: Contribution to journalArticle

Geering, ADW, Maumus, F, Copetti, D, Choisne, N, Zwickl, DJ, Zytnicki, M, McTaggart, AR, Scalabrin, S, Vezzulli, S, Wing, RA, Quesneville, H & Teycheney, PY 2014, 'Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution', Nature Communications, vol. 5, 5269. https://doi.org/10.1038/ncomms6269
Geering, Andrew D W ; Maumus, Florian ; Copetti, Dario ; Choisne, Nathalie ; Zwickl, Derrick J. ; Zytnicki, Matthias ; McTaggart, Alistair R. ; Scalabrin, Simone ; Vezzulli, Silvia ; Wing, Rod A ; Quesneville, Hadi ; Teycheney, Pierre Yves. / Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution. In: Nature Communications. 2014 ; Vol. 5.
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