Endometrial biopsy is an office-based method used to evaluate the tissue lining of the uterus. It is one type of endometrial evaluation recommended by the American College of Obstetricians and Gynecologists for assessment of postmenopausal uterine bleeding, uterine response to hormone therapy, and atypical glandular cells, if present. The technique used is very similar to that used when doing a pelvic examination but adds the components of grasping the cervix with a tenaculum, entering the uterus, and then scraping small samples from the endometrial lining. Complications are rare. This procedure is an important component of office practice for assessing the endometrium.
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