Enhanced endoscopic detection of early colon cancer

Gowri Balachandar, Eugene A Trowers

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Enhanced endoscopic detection of small flat adenomas is becoming increasingly important as they have a reported 14% incidence of dysplasia when compared with 5% incidence in polypoid adenomas of the same size. These lesions even when invasive do not show up against the translucent surrounding mucosa making endoscopic detection difficult. Dye spraying with indigo carmine makes their morphology clear, with well-circumscribed borders. Dye spraying and magnifying endoscopes can be used to observe pit patterns on the surface of the bowel. Combining dye spraying and high-resolution video endoscopy demonstrates well the colorectal epithelial surface. Scanning immersion video endoscopy visualizes the epithelial surface of the colorectal mucosa by high-resolution endoscopy after filling the lumen with water. Endoscopic ultrasound can be used to see if the lesion is intramucosal or not and assess the depth of invasion if malignancy is present. Laser-induced fluorescence spectroscopy has the potential to detect colonic dysplasia in vivo. Combining such technologies with conventional colonoscopy can help in the surveillance of large areas of colonic mucosa for the presence of dysplasia. Guided biopsy can replace random biopsy based on information provided at the time of colonoscopic examination.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages412-419
Number of pages8
Volume3590
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX - San Jose, CA, USA
Duration: Jan 23 1999Jan 24 1999

Other

OtherProceedings of the 1999 Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX
CitySan Jose, CA, USA
Period1/23/991/24/99

Fingerprint

Endoscopy
spraying
Spraying
dyes
cancer
lesions
Dyes
Biopsy
incidence
endoscopes
lumens
high resolution
surveillance
borders
laser induced fluorescence
submerging
Fluorescence spectroscopy
examination
scanning
Ultrasonics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Balachandar, G., & Trowers, E. A. (1999). Enhanced endoscopic detection of early colon cancer. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3590, pp. 412-419). Society of Photo-Optical Instrumentation Engineers.

Enhanced endoscopic detection of early colon cancer. / Balachandar, Gowri; Trowers, Eugene A.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3590 Society of Photo-Optical Instrumentation Engineers, 1999. p. 412-419.

Research output: Chapter in Book/Report/Conference proceedingChapter

Balachandar, G & Trowers, EA 1999, Enhanced endoscopic detection of early colon cancer. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3590, Society of Photo-Optical Instrumentation Engineers, pp. 412-419, Proceedings of the 1999 Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, San Jose, CA, USA, 1/23/99.
Balachandar G, Trowers EA. Enhanced endoscopic detection of early colon cancer. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3590. Society of Photo-Optical Instrumentation Engineers. 1999. p. 412-419
Balachandar, Gowri ; Trowers, Eugene A. / Enhanced endoscopic detection of early colon cancer. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3590 Society of Photo-Optical Instrumentation Engineers, 1999. pp. 412-419
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