Epidemiology of osteoarthritis

Literature update

Ernest R. Vina, Chian K Kwoh

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

Purpose of review The purpose of this review is to highlight recent studies of osteoarthritis epidemiology, including research on prevalence, disease impact, and potential risk factors. Recent findings Osteoarthritis is highly prevalent in the United States and around the globe. It is a leading cause of disability and can negatively impact people's physical and mental well being. Healthcare resources and costs associated with managing the disease can be substantial. There is increasing evidence that there are different osteoarthritis phenotypes that reflect different mechanisms of the disease. Various person-level risk factors are recognized, including sociodemographic characteristics (e.g. female sex, African-American race), genetic predispositions, obesity, diet-related factors, and high bone density/mass. Joint-level risk factors include specific bone/joint shapes, thigh flexor muscle weakness, joint malalignment, participation in certain occupational/sports activities, and joint injury. Recent studies have enhanced our understanding of preradiographic lesions associated with osteoarthritis. Summary Application of these new findings may allow us to develop innovative strategies and novel therapies with the purpose of preventing new disease onset and minimizing disease progression.

Original languageEnglish (US)
Pages (from-to)160-167
Number of pages8
JournalCurrent Opinion in Rheumatology
Volume30
Issue number2
DOIs
StatePublished - Mar 1 2018

Fingerprint

Osteoarthritis
Epidemiology
Joints
Muscle Weakness
Genetic Predisposition to Disease
Thigh
African Americans
Health Care Costs
Bone Density
Sports
Disease Progression
Obesity
Diet
Phenotype
Bone and Bones
Wounds and Injuries
Research
Therapeutics

Keywords

  • epidemiology
  • impact
  • osteoarthritis
  • phenotypes
  • risk factors

ASJC Scopus subject areas

  • Rheumatology

Cite this

Epidemiology of osteoarthritis : Literature update. / Vina, Ernest R.; Kwoh, Chian K.

In: Current Opinion in Rheumatology, Vol. 30, No. 2, 01.03.2018, p. 160-167.

Research output: Contribution to journalReview article

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