Evaluation and treatment of thrombocytopenia in the neonatal intensive care unit

Martha C. Sola, Antonio Del Vecchio, Lisa M Rimsza

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Thrombocytopenia is a very frequent problem among sick neonates, affecting up to 35% of all infants admitted to the NICU. Although multiple clinical conditions have been causally associated with neonatal thrombocytopenia, the cause of the thrombocytopenia is unclear in up to 60% of affected neonates. This article provides neonatologists with a practical approach to the thrombocytopenic neonate, with an emphasis on conditions that could be life-threatening or could have significant implications for further pregnancies. An overview of the current therapeutic modalities is also presented, including a discussion of the possible use of recombinant thrombopoietic cytokines to treat certain groups of thrombocytopenic neonates.

Original languageEnglish (US)
Pages (from-to)655-679
Number of pages25
JournalClinics in Perinatology
Volume27
Issue number3
StatePublished - 2000
Externally publishedYes

Fingerprint

Neonatal Intensive Care Units
Thrombocytopenia
Newborn Infant
Neonatal Alloimmune Thrombocytopenia
Therapeutics
Cytokines
Pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Evaluation and treatment of thrombocytopenia in the neonatal intensive care unit. / Sola, Martha C.; Del Vecchio, Antonio; Rimsza, Lisa M.

In: Clinics in Perinatology, Vol. 27, No. 3, 2000, p. 655-679.

Research output: Contribution to journalArticle

Sola, Martha C. ; Del Vecchio, Antonio ; Rimsza, Lisa M. / Evaluation and treatment of thrombocytopenia in the neonatal intensive care unit. In: Clinics in Perinatology. 2000 ; Vol. 27, No. 3. pp. 655-679.
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