The effect of paddy soils on mycobacillin and versicolin was investigated. Soil inactivated mycobacillin as determined by spectral analysis and microbiological assay. Soil can inactivate mycobacillin only at or above the threshold concentration (125~130 µg per 10 mg of soil), the excess being unreacted. No new peak appears in the ultraviolet spectrum (240~300 nm) while mycobacillin is inactivated. Soil is without any effect on versicolin.
ASJC Scopus subject areas
- Drug Discovery