Evolutionarily conserved mechanisms for the selection and maintenance of behavioural activity

Vincenzo G. Fiore, Raymond J. Dolan, Nicholas J Strausfeld, Frank Hirth

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Survival and reproduction entail the selection of adaptive behavioural repertoires. This selection manifests as phylogenetically acquired activities that depend on evolved nervous system circuitries. Lorenz and Tinbergen already postulated that heritable behaviours and their reliable performance are specified by genetically determined programs. Here we compare the functional anatomy of the insect central complex and vertebrate basal ganglia to illustrate their role in mediating selection and maintenance of adaptive behaviours. Comparative analyses reveal that central complex and basal ganglia circuitries share comparable lineage relationships within clusters of functionally integrated neurons. These clusters are specified by genetic mechanisms that link birth time and order to their neuronal identities and functions. Their subsequent connections and associated functions are characterized by similar mechanisms that implement dimensionality reduction and transition through attractor states, whereby spatially organized parallel-projecting loops integrate and convey sensorimotor representations that select and maintain behavioural activity. In both taxa, these neural systems are modulated by dopamine signalling that also mediates memory-like processes. The multiplicity of similarities between central complex and basal ganglia suggests evolutionarily conserved computational mechanisms for action selection. We speculate that these may have originated from ancestral ground pattern circuitries present in the brain of the last common ancestor of insects and vertebrates.

Original languageEnglish (US)
Article number20150053
JournalPhilosophical transactions of the Royal Society of London. Series B: Biological sciences
Volume370
Issue number1684
DOIs
StatePublished - Dec 19 2015

    Fingerprint

Keywords

  • Action selection
  • Attractor state
  • Basal ganglia
  • Brain evolution
  • Central complex
  • Sensorimotor representation

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this