Evolutionary Quantitative Genetics

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Abstract

Evolutionary quantitative genetics is the study of how complex traits evolve over time. While this field builds on traditional concepts from quantitative genetics widely used by applied breeders and human geneticists (in particular, the inheritance of complex traits), its unique feature is in examining the role of natural selection in changing the population distribution of a complex trait over time. Our review focuses on this role of selection, starting with response under the standard infinitesimal model, in which trait variation is determined by a very large number of loci, each of small effect. We then turn to issues of measuring fitness (and hence natural selection) on both univariate and multivariate traits. We conclude by examining models that treat fitness itself as a complex trait.

Original languageEnglish (US)
Title of host publicationHandbook of Statistical Genetics: Third Edition
PublisherJohn Wiley & Sons, Ltd
Pages533-586
Number of pages54
Volume1
ISBN (Print)9780470058305
DOIs
StatePublished - May 9 2008

Fingerprint

Natural Selection
Fitness
Univariate
Locus
Model
Human
Standards
Concepts
Review

Keywords

  • Artificial selection program
  • Directional selection differential
  • Fisher's genetic decomposition
  • Gametic-phase disequilibrium
  • Infinitesimal model and genotypic values
  • Mean population fitness
  • Multivariate normal
  • Phenotypic and genetic regressions
  • Quadratic selection gradient
  • Robertson-Price identity

ASJC Scopus subject areas

  • Mathematics(all)

Cite this

Walsh, J. B. (2008). Evolutionary Quantitative Genetics. In Handbook of Statistical Genetics: Third Edition (Vol. 1, pp. 533-586). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470061619.ch17

Evolutionary Quantitative Genetics. / Walsh, James "Bruce".

Handbook of Statistical Genetics: Third Edition. Vol. 1 John Wiley & Sons, Ltd, 2008. p. 533-586.

Research output: Chapter in Book/Report/Conference proceedingChapter

Walsh, JB 2008, Evolutionary Quantitative Genetics. in Handbook of Statistical Genetics: Third Edition. vol. 1, John Wiley & Sons, Ltd, pp. 533-586. https://doi.org/10.1002/9780470061619.ch17
Walsh JB. Evolutionary Quantitative Genetics. In Handbook of Statistical Genetics: Third Edition. Vol. 1. John Wiley & Sons, Ltd. 2008. p. 533-586 https://doi.org/10.1002/9780470061619.ch17
Walsh, James "Bruce". / Evolutionary Quantitative Genetics. Handbook of Statistical Genetics: Third Edition. Vol. 1 John Wiley & Sons, Ltd, 2008. pp. 533-586
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