Experimental measurement of the mechanical properties of hypertensive rats based on porohyperelasticity

Mohamed A. Gaballa, Thomas E. Raya, Bruce R. Simon, Yuan Yuan, Steven Goldman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We measured in-vivo poroelastic material constants and hydraulic conductance in intact segments of carotid arteries in normal and spontaneously hypertensive rats (SHRs). The rat carotid arterial wall was treated as a 'porohyperelastic' material. Strain and stress components were calculated based on Fung's pseudo-strain exponential energy function W. The material constants in the SHRs (N=9) were higher (P < 0.05) than in normal rats (N=10). The hydraulic conductivity of the arterial wall, calculated from the filtration data, was lower (P <0.05) at both 50 and 100 mmHg in the SHRs (N=6) when compared to normal rats (N=7).

Original languageEnglish (US)
Title of host publication1991 Advances in Bioengineering
PublisherPubl by ASME
Pages621-622
Number of pages2
ISBN (Print)0791808890
StatePublished - Dec 1 1991
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Atlanta, GA, USA
Duration: Dec 1 1991Dec 6 1991

Publication series

NameAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume20

Conference

ConferenceWinter Annual Meeting of the American Society of Mechanical Engineers
CityAtlanta, GA, USA
Period12/1/9112/6/91

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Gaballa, M. A., Raya, T. E., Simon, B. R., Yuan, Y., & Goldman, S. (1991). Experimental measurement of the mechanical properties of hypertensive rats based on porohyperelasticity. In 1991 Advances in Bioengineering (pp. 621-622). (American Society of Mechanical Engineers, Bioengineering Division (Publication) BED; Vol. 20). Publ by ASME.